Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | SENP1 | Q9P0U3 | 5/20 | 0.43 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985272 | 0.78 | MAOB (0.63) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL19003251 | 0.76 | EGFR (0.68) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL19003252 | 0.72 | RAB9A (0.53) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL19003258 | 0.72 | TRPV1 (0.61) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL29365043 | 0.72 | MAPT (0.55) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL19003253 | 0.72 | MAOB (0.56) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL19003464 | 0.69 | EGFR (0.53) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL28689610 | 0.69 | L3MBTL1 (0.62) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL19003254 | 0.69 | EGFR (0.53) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL19003283 | 0.69 | RAB9A (0.52) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |