Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 12/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985262 | 0.84 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2NAMPTMEN1 | |
| SCHEMBL18985260 | 0.84 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2NAMPTMEN1 | |
| SCHEMBL19003232 | 0.77 | RAB9A (0.53) | HDAC6NPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL19003252 | 0.77 | RAB9A (0.53) | NPC1RAB9ASMN1; SMN2NAMPTMEN1 | |
| SCHEMBL18985266 | 0.74 | HDAC8 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL19003470 | 0.73 | RAB9A (0.65) | NPC1RAB9ASMN1; SMN2MEN1MAPT | |
| SCHEMBL19003361 | 0.73 | NAMPT (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL18985199 | 0.73 | NAMPT (0.48) | NPC1RAB9ASMN1; SMN2NAMPTMEN1 | |
| SCHEMBL4340399 | 0.73 | HDAC1 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4340391 | 0.73 | HDAC1 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |