Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003240 | 0.88 | MAPT (0.57) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL19003252 | 0.86 | RAB9A (0.53) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL19003241 | 0.85 | TGM2 (0.52) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL18985262 | 0.84 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL18985260 | 0.84 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL18985196 | 0.83 | RAB9A (0.54) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL19003263 | 0.78 | SMN1; SMN2 (0.41) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL19003359 | 0.77 | HDAC3 (0.54) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL30595307 | 0.73 | TGM2 (0.67) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL19003470 | 0.73 | RAB9A (0.65) | RAB9ASMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |