Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16101601 | 0.79 | KDR (0.60) | KDREGFRKDM4ENPC1RAB9A | |
| SCHEMBL13991500 | 0.79 | KDR (0.60) | KDREGFRKDM4ENPC1RAB9A | |
| SCHEMBL879570 | 0.76 | KDM4E (0.62) | KDRKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13991503 | 0.75 | RAB9A (0.65) | KDREGFRKDM4ENPC1RAB9A | |
| SCHEMBL18985272 | 0.74 | MAOB (0.63) | EGFRNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL19003356 | 0.74 | TRPV1 (0.49) | EGFRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL846549 | 0.74 | DHODH (0.53) | KDRKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL846550 | 0.74 | DHODH (0.53) | KDRKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29965933 | 0.73 | KDR (0.62) | KDRKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4018954 | 0.73 | KDR (0.62) | KDRKDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |