Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | CDK7 | P50613 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003261 | 0.75 | MMP1 (0.59) | EGFRHDAC1HDAC2RAB9ASMN1; SMN2 | |
| SCHEMBL19003357 | 0.74 | EGFR (0.42) | EGFRRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL19003364 | 0.74 | KDR (0.49) | EGFRHDAC1HDAC2RAB9ASMN1; SMN2 | |
| SCHEMBL19003354 | 0.72 | MMP1 (0.62) | TRPV1EGFRHDAC1HDAC2RAB9A | |
| SCHEMBL19003351 | 0.71 | LMNA (0.50) | EGFRRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL19003363 | 0.70 | RAB9A (0.52) | EGFRRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL27034898 | 0.69 | KDM4E (0.62) | TRPV1RAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL14665804 | 0.68 | ADRA2A (0.50) | MEN1MAPTKMT2AHDAC6MALT1 | |
| SCHEMBL18985272 | 0.68 | MAOB (0.63) | TRPV1EGFRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL19003255 | 0.68 | EGFR (0.47) | EGFRRAB9ASMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |