Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.50 |
| ▸ | TUBB | P07437 | 6/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4823325 | 0.84 | TUBB1 (0.59) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL21845093 | 0.78 | TUBB4A (0.60) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4821487 | 0.78 | MAPT (0.63) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6899973 | 0.75 | TUBB4A (0.50) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Hydroxyphenstatin SCHEMBL30910835 | 0.75 | KDM4E (0.67) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Hydroxyphenstatin SCHEMBL13197632 | 0.75 | KDM4E (0.67) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL26441468 | 0.74 | TUBB1 (0.54) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4819729 | 0.73 | TUBB4A (0.75) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL26441446 | 0.72 | TUBB1 (0.54) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6060599 | 0.72 | ALDH1A1 (0.46) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106861-A1 | COMPOSITIONS OF POLYHYDROXYLATED BENZOPHENONES AND METHODS OF TREATMENT OF NEURODEGENERATIVE DISORDERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-06-22 | — | — | WO | disclosed |