Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003351 | 0.83 | LMNA (0.50) | EGFRTRPM2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL19003298 | 0.80 | EGFR (0.49) | EGFRTRPM2TP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL19003460 | 0.74 | GAA (0.59) | EGFRLMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL19003305 | 0.74 | MMP1 (0.63) | EGFRTP53LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL19003459 | 0.73 | CXCR1 (0.51) | TRPM2TP53LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18985289 | 0.72 | MAOB (0.64) | EGFRTP53LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18985528 | 0.72 | NQO2 (0.56) | EGFRTP53LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL19003466 | 0.72 | NQO2 (0.56) | EGFRTP53LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL19003303 | 0.71 | MAOB (0.52) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL19003456 | 0.71 | MAPT (0.48) | EGFRTP53LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |