Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003305 | 0.88 | MMP1 (0.63) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL19003468 | 0.85 | ALDH1A1 (0.62) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7814186 | 0.75 | GAA (1.00) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7814182 | 0.75 | GAA (1.00) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14478794 | 0.75 | MEN1 (0.67) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL19003469 | 0.74 | EGFR (0.49) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL19003298 | 0.74 | EGFR (0.49) | MAPTALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL14340898 | 0.74 | RAB9A (0.45) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL18985528 | 0.72 | NQO2 (0.56) | MEN1KMT2AMAPTALDH1A1MMP1 | |
| SCHEMBL19003466 | 0.72 | NQO2 (0.56) | MEN1KMT2AMAPTALDH1A1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |