Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003468 | 0.82 | ALDH1A1 (0.62) | LMNAALDH1A1GLAPKMHTT | |
| SCHEMBL124625 | 0.71 | HTT (0.63) | LMNAALDH1A1GLAPKMHTT | |
| SCHEMBL19003459 | 0.69 | CXCR1 (0.51) | LMNAALDH1A1HTTKCNMA1GAA | |
| SCHEMBL7583883 | 0.69 | LMNA (0.58) | LMNAALDH1A1GLAPKMHTT | |
| SCHEMBL13815362 | 0.68 | LMNA (0.78) | LMNAALDH1A1GLAPKMHTT | |
| SCHEMBL22169220 | 0.67 | LMNA (0.58) | LMNAALDH1A1GLAPKMHTT | |
| SCHEMBL3185913 | 0.67 | HTT (0.58) | LMNAALDH1A1GLAPKMHTT | |
| SCHEMBL18985214 | 0.66 | ALDH1A1 (0.65) | LMNAALDH1A1GLAPKMHTT | |
| SCHEMBL19003460 | 0.66 | GAA (0.59) | LMNAALDH1A1GAASMN1; SMN2KMT2A | |
| SCHEMBL18985269 | 0.66 | ALDH1A1 (0.65) | LMNAALDH1A1GLAPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |