Styrene

Styrene

SCHEMBL1900373

C=Cc1ccc(CC2CO2)cc1.C=Cc1ccc(CCO)cc1.C=Cc1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MGLL Q99685 4/20 0.34
SLC5A1 P13866 1/20 0.33
SLC5A2 P31639 1/20 0.33
PSMD14 O00487 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
CA2 P00918 1/20 0.33
ALPL P05186 1/20 0.32
ALPI P09923 1/20 0.32
ALPG P10696 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL306043 0.83 ALDH1A1 (0.44) TDP1ALDH1A1TSHRMEN1KMT2A
SCHEMBL24766198 0.79 ALDH1A1 (0.36) TDP1ALDH1A1TSHRMEN1KMT2A
Phenylethyl Alcohol SCHEMBL2011656 0.78 TDP1 (0.67) TDP1ALDH1A1TSHRPOLBCA2
SCHEMBL394725 0.76 ALDH1A1 (0.52) TDP1ALDH1A1TSHRSLC5A1SLC5A2
SCHEMBL1140784 0.74 ALDH1A1 (0.41) ALDH1A1TSHRMEN1KMT2A
SCHEMBL7518860 0.71 CA2 (0.46) TDP1ALDH1A1TSHRMEN1KMT2A
SCHEMBL7779425 0.71 CA2 (0.46) TDP1ALDH1A1TSHRSLC5A1SLC5A2
Acrylic Acid SCHEMBL8176236 0.71 MGLL (0.43) MEN1KMT2AMGLL
SCHEMBL873444 0.71 SLC6A2 (0.50) TDP1TSHRMEN1KMT2A
SCHEMBL2186411 0.71 SLC6A2 (0.50) TDP1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2327688-A1 PREPARATION OF AZO COMPOUNDS WITH SOLID CATALYSTS Universidad Politécnica De Valencia (UPV) (50%) (ES) 2011-06-01 EP disclosed
EP-2316822-A1 PREPARATION OF CARBAMATES WITH SOLID CATALYSTS Consejo Superior De Investigaciones Científicas (ES) 2011-05-04 EP disclosed