Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394725 | 0.94 | ALDH1A1 (0.52) | CA2ALDH1A1TDP1CYP4F2CYP4A11 | |
| SCHEMBL7779425 | 0.88 | CA2 (0.46) | CA2ALDH1A1TDP1CYP4F2CYP4A11 | |
| SCHEMBL7772314 | 0.82 | CA2 (0.42) | CA2ALDH1A1TDP1CYP4F2CYP4A11 | |
| SCHEMBL2044945 | 0.82 | CA2 (0.65) | CA2ALDH1A1TDP1CYP4F2CYP4A11 | |
| SCHEMBL11041030 | 0.81 | TDP1 (0.48) | CA2ALDH1A1TDP1CYP4F2CYP4A11 | |
| SCHEMBL3627943 | 0.81 | ALDH1A1 (0.48) | CA2ALDH1A1TDP1CYP4F2CYP4A11 | |
| SCHEMBL19738382 | 0.79 | CTSL (0.39) | CA2ALDH1A1CYP4A11HDAC2FFAR1 | |
| SCHEMBL1647493 | 0.79 | ALDH1A1 (0.65) | CA2ALDH1A1TDP1TSHRCA1 | |
| SCHEMBL50012 | 0.79 | ALDH1A1 (0.65) | CA2ALDH1A1TDP1TSHRCA1 | |
| SCHEMBL5033447 | 0.79 | THRB (0.47) | CA2ALDH1A1TSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849246-B1 | Derivatives of 4-vinyl-4'-alpha-hydroxyethyl-biphenyl | CIBA SC HOLDING AG (CH) | 2002-02-06 | — | — | EP | claimed |
| US-5902909-A | Intermediates | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-05-11 | — | — | US | claimed |
| EP-0849246-A2 | Derivatives of 4-vinyl-4'-alpha-hydroxyethyl-biphenyl | Ciba SC Holding AG (CH) | 1998-06-24 | — | — | EP | claimed |
| JP-10226656-A | — | — | None | — | — | JP | disclosed |
| EP-0849246-B1 | Derivatives of 4-vinyl-4'-alpha-hydroxyethyl-biphenyl | CIBA SC HOLDING AG (CH) | 2002-02-06 | — | — | EP | disclosed |
| EP-0849246-B1 | Derivatives of 4-vinyl-4'-alpha-hydroxyethyl-biphenyl | CIBA SC HOLDING AG (CH) | 2002-02-06 | — | — | EP | disclosed |
| US-6194606-B1 | REACTING VINYL-4'-.ALPHA.-HYDROXYETHYL-BIPHENYL COMPOUND WITH DIAZONIUM COMPOUND AND DEHYDRATING IN PRESENCE OF PALLADIUM COMPOUND TO FORM 4,4'-DIVINYL-BIPHENYL COMPOUND | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-02-27 | — | — | US | disclosed |
| US-5902909-A | Intermediates | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-05-11 | — | — | US | disclosed |
| EP-0849246-A3 | Derivatives of 4-vinyl-4'-alpha-hydroxyethyl-biphenyl | Ciba SC Holding AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| JP-H10226656-A | NEW INTERMEDIATE | CIBA SPECIALTY CHEM HOLDING INC | 1998-08-25 | — | — | JP | disclosed |
| EP-0849246-A2 | Derivatives of 4-vinyl-4'-alpha-hydroxyethyl-biphenyl | Ciba SC Holding AG (CH) | 1998-06-24 | — | — | EP | disclosed |
| EP-0849246-A2 | Derivatives of 4-vinyl-4'-alpha-hydroxyethyl-biphenyl | Ciba SC Holding AG (CH) | 1998-06-24 | — | — | EP | disclosed |