Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 6/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18998443 | 0.93 | NPC1 (0.54) | MAPTMAPK1LMNAALOX15HSD17B10 | |
| SCHEMBL10458127 | 0.82 | CES2 (0.59) | MAPTMAPK1LMNAALOX15HSD17B10 | |
| SCHEMBL16147948 | 0.81 | CES2 (0.53) | MAPTMAPK1LMNAALOX15HSD17B10 | |
| SCHEMBL11293300 | 0.81 | MAPT (0.57) | MAPTMAPK1LMNAALOX15HSD17B10 | |
| SCHEMBL6288747 | 0.81 | MAPT (0.51) | MAPTMAPK1LMNAALOX15HSD17B10 | |
| SCHEMBL757101 | 0.80 | CES2 (0.61) | MAPTMAPK1LMNAALOX15HSD17B10 | |
| SCHEMBL2355696 | 0.80 | MAPT (0.70) | MAPTMAPK1LMNAALOX15HSD17B10 | |
| SCHEMBL21480073 | 0.79 | MAPT (0.54) | MAPTMAPK1LMNAALOX15HSD17B10 | |
| SCHEMBL7637140 | 0.79 | CES2 (0.59) | MAPTMAPK1LMNAALOX15HSD17B10 | |
| SCHEMBL10299600 | 0.78 | CES1 (0.62) | MAPTMAPK1LMNAALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184504-B1 | METHODS OF PREPARING ALPHA,BETA-UNSATURATED OR ALPHA-HALO KETONES AND ALDEHYDES | INT FLAVORS & FRAGRANCES INC (US) | 2018-05-02 | — | — | EP | disclosed |
| US-9796653-B2 | Methods of preparing α,β-unsaturated or α-halo ketones and aldehydes | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-10-24 | — | — | US | disclosed |
| EP-3184504-A1 | METHODS OF PREPARING ALPHA,BETA-UNSATURATED OR ALPHA-HALO KETONES AND ALDEHYDES | International Flavors & Fragrances Inc. (US) | 2017-06-28 | — | — | EP | disclosed |
| US-20170174607-A1 | METHODS OF PREPARING a,ß-UNSATURATED OR a-HALO KETONES AND ALDEHYDES | INT FLAVORS & FRAGRANCES INC (US) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174607-A1 | METHODS OF PREPARING a,ß-UNSATURATED OR a-HALO KETONES AND ALDEHYDES | DBH, DOHH, DHCR7 | MAPT 2780/4885MAPK1 3842/4885LMNA 858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.