Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 6/20 | 0.59 |
| ▸ | CA2 | P00918 | 6/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.57 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22548787 | 0.94 | RAB9A (0.59) | CES2CES1CA1CA2PARP10 | |
| SCHEMBL11529955 | 0.94 | PARP10 (0.61) | CES2CES1CA1CA2PARP10 | |
| SCHEMBL10458127 | 0.85 | CES2 (0.59) | CES2CES1CA1CA2PARP10 | |
| SCHEMBL7637140 | 0.85 | CES2 (0.59) | CES2CES1CA1CA2PARP10 | |
| SCHEMBL24813408 | 0.84 | HPGD (0.58) | PARP10PARP4RAB9AMAPTLMNA | |
| SCHEMBL9559909 | 0.83 | CA1 (0.59) | CES2CES1CA1CA2PARP10 | |
| SCHEMBL10031827 | 0.83 | PGR (0.47) | CES2CES1CA2MAPK1LMNA | |
| SCHEMBL4137247 | 0.83 | KDM4E (0.66) | CES2CES1HSD17B10RAB9AALDH1A1 | |
| SCHEMBL18660115 | 0.82 | CES2 (0.55) | CES2CES1CA1CA2PARP10 | |
| SCHEMBL5276595 | 0.81 | ELANE (0.56) | MAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207355-A1 | PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG | L-Base Co., Ltd. (KR) | 2024-06-27 | — | — | US | disclosed |
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-11814372-B2 | Agonists of EPHA and their uses | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-11-14 | — | — | US | disclosed |
| US-11814372-B2 | Agonists of EPHA and their uses | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-11-14 | — | — | US | disclosed |
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| US-20230159587-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER | L-Base Co., Ltd. (KR) | 2023-05-25 | — | — | US | disclosed |
| US-20230159587-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER | L-Base Co., Ltd. (KR) | 2023-05-25 | — | — | US | disclosed |
| US-20220098585-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-03-31 | — | — | US | disclosed |
| US-7253204-B2 | Antiproliferative agents | METHYLGENE INC. (CA) | 2007-08-07 | — | — | US | disclosed |
| WO-2007069777-A2 | FUNGICIDAL COMPOSITION CONTAINING CARBOXYLIC ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2007-06-21 | — | — | WO | disclosed |
| EP-1776011-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006016708-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-02-16 | — | — | WO | disclosed |
| US-5573712-A | PHOTOCHROMIC ARTICLE COMPRISING ORGANIC HOST AND THE PHOTOCHROMIC NAPHTHOPYRAN | TRANSITIONS OPTICAL, INC. (US) | 1996-11-12 | — | — | US | disclosed |
| US-5458814-A | Ophthalmic lenses | TRANSITIONS OPTICAL, INC. (US) | 1995-10-17 | — | — | US | disclosed |
| WO-1995016215-A1 | NOVEL SUBSTITUTED NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1995-06-15 | — | — | WO | disclosed |
| US-4935510-A | Thiation process | ETHYL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4663452-A | Thiation process | ETHYL CORPORATION (US) | 1987-05-05 | — | — | US | disclosed |
| US-4043790-A | 2-OR 4-SUBSTITUTED PYRIDINE METHANE OR PYRIDINE METHANOL, NONHERBICIDAL | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | TRIM33, TRIM28, TRIM4 | CES2 3614/4885CES1 1784/4885CA1 4391/4885 |
| US-20230159587-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER | VIP, QPCT, TPT1 | CES2 4869/4885CES1 3055/4885CA1 2893/4885 |
| US-20240207355-A1 | PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG | ALPG, SLC11A2, SGTA | CES2 4879/4885CES1 4726/4885CA1 2208/4885 |
| US-11814372-B2 | Agonists of EPHA and their uses | EPHA2, EPHA7, EPHA1 | CES2 2431/4885CES1 1153/4885CA1 2491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.