Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | GMNN | O75496 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28591577 | 0.83 | S1PR1 (0.65) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL3777505 | 0.80 | S1PR1 (0.68) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL15235841 | 0.78 | SPHK2 (0.61) | ALDH1A1SPHK2SPHK1MEN1KMT2A | |
| SCHEMBL22986833 | 0.78 | SPHK2 (0.61) | ALDH1A1SPHK2SPHK1MEN1KMT2A | |
| SCHEMBL1512942 | 0.78 | SPHK2 (0.61) | ALDH1A1SPHK2SPHK1MEN1KMT2A | |
| SCHEMBL19005913 | 0.78 | S1PR1 (0.52) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL3772519 | 0.77 | LPAR3 (0.51) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| Iodide SCHEMBL5689882 | 0.77 | SPHK2 (0.59) | ALDH1A1SPHK2SPHK1MEN1KMT2A | |
| Phosphoric Acid SCHEMBL6665386 | 0.75 | MAPT (0.54) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL13161631 | 0.68 | SPHK1 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696247-B2 | Lipid-based nitric oxide donors | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-04-13 | — | — | US | disclosed |
| US-20100062055-A1 | LIPID-BASED NITRIC OXIDE DONORS | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-03-11 | — | — | US | disclosed |
| EP-1343485-B1 | Drug delivery system comprising a lipid-based nitric oxide donor | BOSTON SCIENT LTD (BB) | 2010-01-27 | — | — | EP | disclosed |
| US-20040259840-A1 | Lipid-based nitric oxide donors | HERRMANN ROBERT A (US) | 2004-12-23 | — | — | US | disclosed |
| US-6780849-B2 | Lipid-based nitric oxide donors | SCIMED LIFE SYSTEMS, INC. | 2004-08-24 | — | — | US | disclosed |
| EP-1343485-A2 | LIPID-BASED NITRIC OXIDE DONORS | Boston Scientific Limited (BB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002056874-A2 | LIPID-BASED NITRIC OXIDE DONORS | SCIMED LIFE SYSTEMS, INC. (US) | 2002-07-25 | — | — | WO | disclosed |
| US-20020082221-A1 | Lipid-based nitric oxide donors | SCIMED LIFE SYSTEMS, INC. | 2002-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082221-A1 | Lipid-based nitric oxide donors | NOS1, NOS3, NOS2 | S1PR1 40/4885ALDH1A1 1080/4885S1PR4 93/4885 |
| US-20100062055-A1 | LIPID-BASED NITRIC OXIDE DONORS | NOS1, NOS2, MGLL | S1PR1 27/4885ALDH1A1 1014/4885S1PR4 64/4885 |
| US-20040259840-A1 | Lipid-based nitric oxide donors | NOS1, NOS2, NOS3 | S1PR1 26/4885ALDH1A1 913/4885S1PR4 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.