Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005998 | 0.91 | LMNA (0.39) | MAPTLMNAALDH1A1ALPGPKM | |
| SCHEMBL19005979 | 0.85 | HTT (0.36) | MAPTALDH1A1NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL18987254 | 0.82 | MAPT (0.37) | MAPTLMNAALDH1A1ALPGPKM | |
| SCHEMBL19005974 | 0.80 | LMNA (0.38) | MAPTLMNAALDH1A1ALPGPKM | |
| SCHEMBL19005960 | 0.78 | REN (0.34) | LMNASMN1; SMN2KMT2A | |
| SCHEMBL19005961 | 0.76 | REN (0.36) | — | |
| SCHEMBL18987377 | 0.76 | REN (0.36) | — | |
| SCHEMBL19005968 | 0.75 | GAA (0.37) | MAPTALDH1A1NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL996841 | 0.75 | MAPT (0.55) | MAPTLMNAALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL997072 | 0.73 | MAPT (0.55) | MAPTLMNAALDH1A1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | disclosed |