Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005964 | 0.91 | MAPT (0.38) | LMNAALDH1A1PKMMAPTALPG | |
| SCHEMBL19005968 | 0.84 | GAA (0.37) | ALDH1A1MAPTNPSR1SMN1; SMN2GAA | |
| SCHEMBL19005974 | 0.81 | LMNA (0.38) | LMNAALDH1A1PKMMAPTALPG | |
| SCHEMBL18987254 | 0.80 | MAPT (0.37) | LMNAALDH1A1PKMMAPTALPG | |
| SCHEMBL19005979 | 0.75 | HTT (0.36) | ALDH1A1MAPTNPSR1SMN1; SMN2GAA | |
| SCHEMBL996693 | 0.74 | TUBB4A (0.61) | LMNAALDH1A1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL996692 | 0.74 | TUBB4A (0.61) | LMNAALDH1A1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL8973887 | 0.70 | SMN1; SMN2 (0.57) | LMNAALDH1A1PKMNPSR1SMN1; SMN2 | |
| SCHEMBL18987379 | 0.69 | CYP19A1 (0.46) | LMNAMAPTGAAMEN1KMT2A | |
| SCHEMBL19005960 | 0.69 | REN (0.34) | LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | disclosed |