Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005979 | 0.90 | HTT (0.36) | GAAHTTMAPTMAPK1APAF1 | |
| SCHEMBL19005998 | 0.84 | LMNA (0.39) | GAAHTTMAPTMEN1KMT2A | |
| SCHEMBL19005967 | 0.79 | GAA (0.36) | GAAHTTMAPTMAPK1APAF1 | |
| SCHEMBL19005918 | 0.77 | HTR1A (0.38) | GAAHTTMAPTMAPK1APAF1 | |
| SCHEMBL19005964 | 0.75 | MAPT (0.38) | GAAHTTMAPTMEN1KMT2A | |
| SCHEMBL19005965 | 0.75 | CSNK2A1 (0.35) | GAAHTTMAPTMEN1KMT2A | |
| SCHEMBL19005960 | 0.72 | REN (0.34) | KMT2ASMN1; SMN2KDM4EMTNR1AMTNR1B | |
| SCHEMBL19005957 | 0.72 | HDAC1 (0.36) | GAAMEN1KMT2ANPSR1TUBB4A | |
| SCHEMBL18987377 | 0.71 | REN (0.36) | MTNR1AMTNR1B | |
| SCHEMBL19005961 | 0.71 | REN (0.36) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | disclosed |