Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19006007 | 0.90 | CYP3A4 (0.39) | SIGMAR1KCNH2TMEM97ADRB2GAA | |
| SCHEMBL18987263 | 0.90 | KCNH2 (0.34) | SIGMAR1KCNH2TMEM97STAT3KDM4E | |
| SCHEMBL18987234 | 0.84 | PPARG (0.32) | PPARGPPARA | |
| SCHEMBL19005915 | 0.84 | PDE4A (0.33) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL19005966 | 0.82 | CYP3A4 (0.38) | SIGMAR1KCNH2TMEM97GAAMEN1 | |
| SCHEMBL19005967 | 0.82 | GAA (0.36) | GAAMEN1KMT2AKDM4EUSP2 | |
| SCHEMBL19005989 | 0.81 | HDAC1 (0.37) | SIGMAR1KCNH2GAAMEN1KMT2A | |
| SCHEMBL19005987 | 0.78 | HDAC1 (0.38) | GAAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL19005918 | 0.73 | HTR1A (0.38) | SIGMAR1KCNH2TMEM97GAAMEN1 | |
| SCHEMBL19005956 | 0.73 | HTR1A (0.36) | SIGMAR1KCNH2GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | disclosed |