Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005991 | 0.86 | MTNR1A (0.34) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL19006008 | 0.86 | HDAC1 (0.36) | HDAC1HDAC2PPARAMAPTTSHR | |
| SCHEMBL19005997 | 0.84 | SIGMAR1 (0.34) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL19005987 | 0.84 | HDAC1 (0.38) | HDAC1HDAC2MAPTTSHRSMN1; SMN2 | |
| SCHEMBL19006007 | 0.83 | CYP3A4 (0.39) | ADRB2TSHRLMNA | |
| SCHEMBL18987263 | 0.82 | KCNH2 (0.34) | PDE4D | |
| SCHEMBL19006005 | 0.79 | HTR1A (0.34) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL19005966 | 0.78 | CYP3A4 (0.38) | MAPTTSHRLMNA | |
| SCHEMBL18987234 | 0.75 | PPARG (0.32) | PPARATSHRLMNAPPARG | |
| SCHEMBL19005992 | 0.74 | HDAC1 (0.39) | PDE4APDE4BPDE4CPDE4DHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | disclosed |