Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.31 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.31 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1076165 | 0.91 | POLB (0.36) | EGLN2PIK3CDPIK3CAGRM1GRM5 | |
| SCHEMBL1900602 | 0.86 | TDP2 (0.42) | EGLN2PIK3CDGRM5HPGDCYP1A2 | |
| SCHEMBL1074241 | 0.81 | SMN1; SMN2 (0.36) | BRD9HPGDCYP1A2USP2HSD17B10 | |
| SCHEMBL1902028 | 0.80 | GRM5 (0.45) | EGLN2PIK3CDPIK3CAGRM5AR | |
| SCHEMBL1901532 | 0.80 | GRM5 (0.36) | EGLN2GRM5KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL1904366 | 0.77 | ALDH1A1 (0.35) | EGLN2PIK3CDPIK3CAGRM5HPGD | |
| SCHEMBL1074256 | 0.77 | GRM1 (0.43) | BRD9GRM1KCNH2 | |
| SCHEMBL1074623 | 0.77 | PIK3CA (0.41) | PIK3CAGRM1KCNH2 | |
| SCHEMBL1074860 | 0.76 | POLB (0.36) | EGLN2PIK3CAGRM1GRM5KCNH2 | |
| SCHEMBL19967260 | 0.75 | HTT (0.41) | PIK3CDPIK3CAGRM5KCNH2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056463-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |