Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.38 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751788 | 0.80 | PIK3CG (0.38) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL13828431 | 0.80 | LRRK2 (0.45) | ALDH1A1KDM4ESMN1; SMN2GAALMNA | |
| SCHEMBL8237076 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2GAALMNA | |
| SCHEMBL8243678 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2GAALMNA | |
| SCHEMBL19185310 | 0.73 | MAPK13 (0.38) | ALDH1A1KDM4ESMN1; SMN2GAALMNA | |
| SCHEMBL14983681 | 0.72 | YTHDC1 (0.44) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL6719246 | 0.71 | PIK3CG (0.33) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL21048252 | 0.71 | PIK3CG (0.37) | KDM4ETDP1LRRK2 | |
| SCHEMBL12186825 | 0.71 | LRRK2 (0.47) | ALDH1A1KDM4EGAAHSD17B10HTT | |
| SCHEMBL1109104 | 0.71 | KDM4E (0.39) | ALDH1A1KDM4ESMN1; SMN2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |