SCHEMBL1900629

SCHEMBL1900629

O=C(F)c1c(F)c(F)c(C(=O)F)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
HTT P42858 2/20 0.36
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA4 P22748 2/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
MAPK1 P28482 1/20 0.33
GAA P10253 1/20 0.32
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TAS1R3 Q7RTX0 2/20 0.30
TAS1R1 Q7RTX1 2/20 0.30
TAS1R2 Q8TE23 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL317184 0.96 CES2 (0.43) CES2CES1HTTCA1CA2
SCHEMBL6448128 0.89 CES2 (0.43) CES2CES1HTTCA1CA2
SCHEMBL9320500 0.85 CES2 (0.32) CES2CES1HTT
SCHEMBL10709506 0.83 CES2 (0.46) CES2CES1
SCHEMBL10710744 0.81 CES2 (0.56) CES2CES1HTTCA1CA2
SCHEMBL9073432 0.81 SMN1; SMN2 (0.44) CES2CES1SMN1; SMN2
SCHEMBL9748198 0.81 TAS1R3 (0.44) CES2CES1HTTPKMSMN1; SMN2
SCHEMBL5274780 0.79 CA1 (0.37) CA1CA2
SCHEMBL9693672 0.78 CA1 (0.61) CES2CES1CA1CA2CA4
SCHEMBL9693234 0.78 CES2 (0.42) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2471766-B1 Process for producing 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol SUMITOMO CHEMICAL CO (JP) 2013-09-04 EP claimed
US-20130060032-A1 POTASSIUM FLUORIDE DISPERSION AND PROCESS FOR PRODUCING FLUORINE-CONTAINING ORGANIC COMPOUND USING THE SAME HAGIYA KOJI (JP) 2013-03-07 US claimed
EP-1961729-B1 METHOD FOR PRODUCING TETRAFLUOROTEREPHTHALIC ACID DIFLUORIDE SUMITOMO CHEMICAL CO (JP) 2012-09-26 EP claimed
EP-2471766-A1 Process for producing 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol Sumitomo Chemical Company, Limited (JP) 2012-07-04 EP claimed
US-8039680-B2 Process for producing 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-18 US claimed
US-8017798-B2 Method for producing tetrafluoroterephthalic acid difluoride SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-13 US claimed
US-20110112321-A1 ALKALI METAL FLUORIDE DISPERSION AND PROCESS FOR PRODUCING FLUORINE-CONTAINING ORGANIC COMPOUND USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-12 US claimed
US-20100324344-A1 PROCESS FOR PRODUCING 4-METHYL-2,3,5,6-TETRAFLUOROBENZYL ALCOHOL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-23 US claimed
EP-2192087-A1 ALKALI METAL FLUORIDE DISPERSION, AND PROCESS FOR PRODUCTION OF FLUORINATED ORGANIC COMPOUND USING THE SAME Sumitomo Chemical Company, Limited (JP) 2010-06-02 EP claimed
EP-2123624-A1 METHOD FOR PRODUCING 4-METHYL-2,3,5,6-TETRAFLUOROBENZYL ALCOHOL Sumitomo Chemical Company, Limited (JP) 2009-11-25 EP claimed
US-20090227810-A1 METHOD FOR PRODUCING TETRAFLUOROTEREPHTHALIC ACID DIFLUORIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-10 US claimed
US-20090099387-A1 POTASSIUM FLUORIDE DISPERSION SOLUTION, AND PROCESS FOR PRODUCTION OF FLUORINATED ORGANIC COMPOUND USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-16 US claimed
EP-2011764-A1 POTASSIUM FLUORIDE DISPERSION SOLUTION, AND PROCESS FOR PRODUCTION OF FLUORINATED ORGANIC COMPOUND USING THE SAME Sumitomo Chemical Company, Limited (JP) 2009-01-07 EP claimed
EP-1961729-A1 METHOD FOR PRODUCING TETRAFLUOROTEREPHTHALIC ACID DIFLUORIDE Sumitomo Chemical Company, Limited (JP) 2008-08-27 EP claimed
EP-0140482-B1 FLUORINATION PROCESS FOR THE PRODUCTION OF NUCLEAR FLUORINATED PHTHALOYL- AND TEREPHTHALOYL FLUORIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-01-13 EP claimed
EP-0140482-A2 Fluorination process for the production of nuclear fluorinated phthaloyl- and terephthaloyl fluorides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-05-08 EP claimed
US-12252583-B2 Method of making mixture of polymers SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2025-03-18 US disclosed
US-20210246264-A1 METHOD OF MAKING MIXTURE OF POLYMERS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2021-08-12 US disclosed
EP-0140482-A2 Fluorination process for the production of nuclear fluorinated phthaloyl- and terephthaloyl fluorides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-05-08 EP disclosed
EP-0140482-A2 Fluorination process for the production of nuclear fluorinated phthaloyl- and terephthaloyl fluorides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-05-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227810-A1 METHOD FOR PRODUCING TETRAFLUOROTEREPHTHALIC ACID DIFLUORIDE DDT, DGKA, FGFR1 CES2 2711/4885CES1 3544/4885HTT 96/4885
US-20110112321-A1 ALKALI METAL FLUORIDE DISPERSION AND PROCESS FOR PRODUCING FLUORINE-CONTAINING ORGANIC COMPOUND USING THE SAME AFF1, AFF4, AFF2 CES2 3277/4885CES1 3417/4885HTT 4837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.