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SCHEMBL19007776

SCHEMBL19007776

CCC(C)COc1cc2c(cc1OCCC(C)C)C1(c3cc(/C=C/c4ccc(C)cc4)ccc3-c3ccc(/C=C/c4ccc(C)cc4)cc31)c1cc(OCCC(C)C)c(OCC(C)CC)cc1-2

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ IGF1R P08069 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ PDK2 Q15119 1/20 0.30
▸ NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14306944 0.93 NFE2L2 (0.34) IGF1RPDK2NFE2L2
SCHEMBL18062069 0.92 PDE4B (0.35) IGF1RMAPTNFE2L2
SCHEMBL17849115 0.90 PDK2 (0.36) IGF1RSMN1; SMN2PDK2NFE2L2
SCHEMBL679086 0.83 TUBB4A (0.34) IGF1RPDK2
SCHEMBL13956686 0.82 — —
SCHEMBL12595641 0.80 TLR8 (0.36) IGF1RMAPTKMT2APDK2
SCHEMBL4546505 0.80 TLR8 (0.36) IGF1RMAPTKMT2APDK2
SCHEMBL14461295 0.79 ALDH1A1 (0.38) IGF1RMAPTKMT2APDK2
SCHEMBL12027393 0.79 ALDH1A1 (0.38) IGF1RMAPTKMT2APDK2
SCHEMBL18718107 0.79 ALDH1A1 (0.38) IGF1RMAPTKMT2APDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10333068-B2 White light emission MERCK PATENT GMBH (DE) 2019-06-25 — — US disclosed
US-20170179392-A1 WHITE LIGHT EMISSION MERCK PATENT GMBH (DE) 2017-06-22 — — US disclosed
US-20170179392-A1 WHITE LIGHT EMISSION MERCK PATENT GMBH (DE) 2017-06-22 — — US disclosed