SCHEMBL19009367

SCHEMBL19009367

BCn1c2ccccc2c2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.64
CYP2C19 P33261 1/20 0.64
CYP19A1 P11511 1/20 0.54
BACE1 P56817 2/20 0.52
KDM4E B2RXH2 4/20 0.50
ALDH1A1 P00352 2/20 0.50
FABP4 P15090 3/20 0.47
FABP5 Q01469 3/20 0.47
FABP3 P05413 1/20 0.47
P2RX4 Q99571 1/20 0.47
GPR3 P46089 1/20 0.46
GLA P06280 1/20 0.45
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HDAC6 Q9UBN7 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
HBB P68871 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22596778 0.85 CYP1A2 (0.48) CYP1A2CYP2C19CYP19A1BACE1KDM4E
SCHEMBL14208728 0.82 KDM4E (0.60) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL14464150 0.80 CYP1A2 (0.58) CYP1A2CYP2C19CYP19A1BACE1KDM4E
SCHEMBL2460596 0.79 CYP1A2 (0.64) CYP1A2CYP2C19CYP19A1BACE1KDM4E
SCHEMBL9768532 0.78 CYP1A2 (0.70) CYP1A2CYP2C19CYP19A1BACE1KDM4E
SCHEMBL5134759 0.78 CYP1A2 (1.00) CYP1A2CYP2C19CYP19A1BACE1KDM4E
SCHEMBL14464145 0.77 FABP4 (0.56) CYP1A2CYP2C19FABP4FABP5FABP3
SCHEMBL13320171 0.74 CYP1A2 (0.64) CYP1A2CYP2C19CYP19A1BACE1KDM4E
SCHEMBL15930272 0.74 CYP1A2 (0.64) CYP1A2CYP2C19CYP19A1BACE1KDM4E
SCHEMBL22498229 0.74 CYP1A2 (0.64) CYP1A2CYP2C19CYP19A1BACE1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170174705-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170174705-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, C9, CRY2 CYP1A2 945/4885CYP2C19 265/4885CYP19A1 82/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.