Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30038698 | 0.80 | CYP1A2 (0.58) | CYP1A2CYP2C19CYP19A1BACE1KDM4E | |
| SCHEMBL1478604 | 0.80 | CYP1A2 (0.58) | CYP1A2CYP2C19CYP19A1BACE1KDM4E | |
| SCHEMBL19009367 | 0.79 | CYP1A2 (0.64) | CYP1A2CYP2C19CYP19A1BACE1KDM4E | |
| SCHEMBL9768532 | 0.78 | CYP1A2 (0.70) | CYP1A2CYP2C19CYP19A1BACE1KDM4E | |
| SCHEMBL5134759 | 0.78 | CYP1A2 (1.00) | CYP1A2CYP2C19CYP19A1BACE1KDM4E | |
| SCHEMBL13957035 | 0.77 | CYP19A1 (0.86) | CYP1A2CYP2C19CYP19A1P2RX4HDAC6 | |
| SCHEMBL2700703 | 0.77 | FABP4 (0.56) | CYP1A2CYP2C19CYP19A1FABP4FABP5 | |
| SCHEMBL541993 | 0.77 | FABP4 (0.56) | CYP1A2CYP2C19CYP19A1FABP4FABP5 | |
| SCHEMBL30007452 | 0.75 | CYP19A1 (1.00) | CYP1A2CYP2C19CYP19A1KDM4EP2RX4 | |
| SCHEMBL151053 | 0.75 | CYP19A1 (1.00) | CYP1A2CYP2C19CYP19A1KDM4EP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109516946-A | A method of preparing carbazole compound | 上海交通大学 | 2019-03-26 | — | — | CN | disclosed |
| CN-104370801-B | Carbazole compound and application thereof | 东曹株式会社 | 2017-11-03 | — | — | CN | disclosed |
| US-20170298118-A1 | METHODS FOR SCREENING ANTIBODIES | SEATTLE GENETICS, INC. (US) | 2017-10-19 | — | — | US | disclosed |
| US-9725500-B2 | Methods for screening antibodies | SEATTLE GENETICS, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| CN-104326968-B | Carbazole compound and use thereof | 东曹株式会社 | 2017-04-12 | — | — | CN | disclosed |
| EP-2542576-B1 | METHODS FOR SCREENING ANTIBODIES | SEATTLE GENETICS INC (US) | 2016-04-20 | — | — | EP | disclosed |
| US-9278124-B2 | Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods | HALOZYME, INC. (US) | 2016-03-08 | — | — | US | disclosed |
| CN-104370801-A | Carbazole compound, and use therefor | TOSOH CORP | 2015-02-25 | — | — | CN | disclosed |
| CN-104326968-A | Carbazole compound and use thereof | TOSOH CORP | 2015-02-04 | — | — | CN | disclosed |
| WO-2014062856-A1 | HYPOXIA AND HYALURONAN AND MARKERS THEREOF FOR DIAGNOSIS AND MONITORING OF DISEASES AND CONDITIONS AND RELATED METHODS | HALOZYME, INC. (US) | 2014-04-24 | — | — | WO | disclosed |
| EP-2542576-A1 | METHODS FOR SCREENING ANTIBODIES | Seattle Genetics, Inc. (US) | 2013-01-09 | — | — | EP | disclosed |
| US-20120322686-A1 | METHODS FOR SCREENING ANTIBODIES | SEATTLE GENETICS, INC. (US) | 2012-12-20 | — | — | US | disclosed |
| WO-2011109308-A1 | METHODS FOR SCREENING ANTIBODIES | SEATTLE GENETICS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298118-A1 | METHODS FOR SCREENING ANTIBODIES | FCGR2A, FCGR3B, FCGR1A | CYP1A2 4289/4885CYP2C19 4671/4885CYP19A1 3366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.