SCHEMBL19009728

SCHEMBL19009728

c1ccc(-c2nc3c4ccccc4c4ccccc4c3c3c2cc(-c2c4ccccc4c(-c4cccc5c4oc4ccccc45)c4ccccc24)c2ccccc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.40
MAPT P10636 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CSF1R P07333 1/20 0.36
PDGFRB P09619 1/20 0.36
KIT P10721 1/20 0.36
FLT3 P36888 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
GGPS1 O95749 1/20 0.35
ADORA2A P29274 1/20 0.34
PRKDC P78527 5/20 0.34
PIK3CD O00329 1/20 0.34
PIK3CB P42338 1/20 0.34
PTGES2 Q9H7Z7 1/20 0.33
PTGER1 P34995 1/20 0.32
ATM Q13315 1/20 0.31
HPGD P15428 2/20 0.30
KDM4E B2RXH2 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19009721 0.87 ALOX5 (0.41) ALOX5MAPTMEN1KMT2ACSF1R
SCHEMBL17034992 0.86 ALOX5 (0.41) ALOX5MAPTMEN1KMT2ACSF1R
SCHEMBL18907187 0.86 ALOX5 (0.38) ALOX5MAPTMEN1KMT2ACSF1R
SCHEMBL19009766 0.82 ALDH1A1 (0.37) MAPTMEN1KMT2AATMHPGD
SCHEMBL12011490 0.79 ALOX5 (0.50) ALOX5MAPTMEN1KMT2AGGPS1
SCHEMBL17915360 0.79 ALOX5 (0.48) ALOX5MAPTMEN1KMT2ACSF1R
SCHEMBL17035091 0.78 ALOX5 (0.40) ALOX5MAPTMEN1KMT2ACSF1R
SCHEMBL14826934 0.77 ALOX5 (0.49) ALOX5MAPTMEN1KMT2ACSF1R
SCHEMBL14826940 0.77 ALOX5 (0.44) ALOX5MAPTMEN1KMT2ACSF1R
SCHEMBL12268513 0.77 ALOX5 (0.52) ALOX5MAPTMEN1KMT2ACSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 ALOX5 1185/4885MAPT 1824/4885MEN1 611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.