SCHEMBL19009801

SCHEMBL19009801

O=P(c1ccccc1)(c1ccccc1)c1c2ccccc2c(-c2cc3nc(-c4ccccc4)c4c5ccccc5c5ccccc5c4c3c3ccccc23)c2ccccc12

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
TOP1 P11387 1/20 0.32
PDE10A Q9Y233 2/20 0.32
DHODH Q02127 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
TOP2A P11388 1/20 0.30
ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19009816 0.90 TOP2A (0.33) TOP1ALDH1A1TOP2A
SCHEMBL19009845 0.87 NPSR1 (0.35) LMNANPSR1ALDH1A1HPGDADORA2A
SCHEMBL17034979 0.84 LMNA (0.37) LMNAPDE10ADHODHNPSR1TSHR
SCHEMBL19009800 0.84 TOP1 (0.38) LMNATOP1PDE10ADHODHTSHR
SCHEMBL19009799 0.83 TOP1 (0.35) LMNATOP1PDE10ADHODHTSHR
SCHEMBL19009807 0.82 LMNA (0.33) LMNATOP1PDE10ADHODHNPSR1
SCHEMBL19009814 0.81 TOP1 (0.37) LMNATOP1PDE10ADHODHTSHR
SCHEMBL19009835 0.81 TOP1 (0.34) LMNATOP1PDE10ADHODHTSHR
SCHEMBL19009823 0.80 CYP11B1 (0.35) LMNATOP1PDE10ADHODHTSHR
SCHEMBL19009771 0.80 TOP1 (0.33) TOP1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 LMNA 1959/4885TOP1 898/4885PDE10A 2487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.