SCHEMBL19009807

SCHEMBL19009807

O=P(c1ccccc1)(c1ccccc1)c1c2ccccc2c(-c2ccc3c(c2)nc(-c2ccccc2)c2c4ccccc4c4ccccc4c32)c2ccccc12

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
DHODH Q02127 4/20 0.32
DHFR P00374 1/20 0.32
TOP1 P11387 1/20 0.31
PDE10A Q9Y233 2/20 0.31
NPSR1 Q6W5P4 1/20 0.31
AKR1B10 O60218 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
TSHR P16473 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17300241 0.87 DHFR (0.40) LMNADHODHDHFRPDE10ACSNK2A2
SCHEMBL17035054 0.86 ESR1 (0.34) LMNAESR1ESR2DHODHCSNK2A2
SCHEMBL17300246 0.84 DHFR (0.39) LMNADHODHDHFRTOP1PDE10A
SCHEMBL17300243 0.83 DHODH (0.36) LMNADHODHDHFRPDE10ACSNK2A2
SCHEMBL19009821 0.82 NPSR1 (0.36) LMNADHODHPDE10ANPSR1AKR1B10
SCHEMBL19009801 0.82 LMNA (0.34) LMNADHODHTOP1PDE10ANPSR1
SCHEMBL19009757 0.81 TOP1 (0.35) TOP1NPSR1
SCHEMBL17300237 0.81 DHODH (0.40) LMNADHODHDHFRPDE10ATSHR
SCHEMBL19009803 0.81 TOP1 (0.35) LMNADHODHDHFRTOP1PDE10A
SCHEMBL17300231 0.80 DHODH (0.42) LMNADHODHPDE10ATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 LMNA 1959/4885ESR1 227/4885ESR2 470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.