SCHEMBL19009873

SCHEMBL19009873

Brc1ccc2c(c1)c(-c1ccccc1)nc1c3ccccc3c3ccccc3c21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRNP P04156 1/20 0.48
DCLK1 O15075 1/20 0.46
PRKD3 O94806 1/20 0.46
MAP4K4 O95819 1/20 0.46
CHEK2 O96017 1/20 0.46
CSF1R P07333 1/20 0.46
FER P16591 1/20 0.46
CDK2 P24941 1/20 0.46
MARK3 P27448 1/20 0.46
FLT4 P35916 1/20 0.46
FLT3 P36888 1/20 0.46
MAPK9 P45984 1/20 0.46
CSNK1D P48730 1/20 0.46
CLK2 P49760 1/20 0.46
CSNK2A1 P68400 1/20 0.46
CSNK1G2 P78368 1/20 0.46
MAP4K2 Q12851 1/20 0.46
STK3 Q13188 1/20 0.46
CAMK2B Q13554 1/20 0.46
CAMK2G Q13555 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17915419 0.83 CYP1A2 (0.39) PRNPPOLBRXFP1MAPTADORA2A
SCHEMBL19009869 0.83 IDO1 (0.43) KMT2ARXFP1MAPTMEN1
SCHEMBL21537425 0.80 CYP2A6 (0.43) PRNPDCLK1PRKD3MAP4K4CHEK2
SCHEMBL18647353 0.79 PRNP (0.55) PRNPDCLK1PRKD3MAP4K4CHEK2
SCHEMBL18808966 0.79 TYMS (0.36) PRNPKMT2AMAPTTHRBMEN1
SCHEMBL17915328 0.79 NUDT1 (0.40) ATMKMT2AMAPTMEN1ADORA2A
SCHEMBL18647352 0.78 PRNP (0.62) PRNPDCLK1PRKD3MAP4K4CHEK2
SCHEMBL16381074 0.78 PTGFR (0.40) PRNPDCLK1PRKD3MAP4K4CHEK2
SCHEMBL17300262 0.78 PRNP (0.48) PRNPDCLK1PRKD3MAP4K4CHEK2
SCHEMBL17300255 0.78 PRNP (0.48) PRNPDCLK1PRKD3MAP4K4CHEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 PRNP 4353/4885DCLK1 940/4885PRKD3 4646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.