Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819025 | 0.97 | ESR1 (0.39) | THRBALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL20110391 | 0.94 | KDM4E (0.34) | THRBALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL21829175 | 0.92 | POLB (0.41) | THRBSMN1; SMN2LMNAESR1ESR2 | |
| SCHEMBL2231834 | 0.88 | ESR1 (0.46) | THRBALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL4948908 | 0.87 | ESR1 (0.37) | THRBALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL29499719 | 0.86 | KDM4E (0.40) | ALDH1A1KDM4ESMN1; SMN2ESR1ESR2 | |
| SCHEMBL2230816 | 0.86 | KDM4E (0.40) | ALDH1A1KDM4ESMN1; SMN2ESR1ESR2 | |
| SCHEMBL29499715 | 0.86 | KDM4E (0.40) | ALDH1A1KDM4ESMN1; SMN2ESR1ESR2 | |
| SCHEMBL14889149 | 0.85 | POLB (0.45) | THRBALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL6321833 | 0.85 | PPARG (0.36) | THRBESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180163135-A1 | LIQUID CRYSTAL POLYMERIZED FILMS USING ALIGNMENT FILM AND POLYMERIZABLE LIQUID CRYSTAL COMPOSTION | JNC CORPORATION (JP) | 2018-06-14 | — | — | US | disclosed |
| US-20180079957-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTALLINE POLYMERS, PHASE DIFFERENCE FILM AND DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| US-20170174992-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, COMPOSITION, LIQUID CRYSTAL POLYMERIZATION FILM-KIND THEREOF AND USE THEREOF | JNC CORPORATION (JP) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174992-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, COMPOSITION, LIQUID CRYSTAL POLYMERIZATION FILM-KIND THEREOF AND USE THEREOF | RCC1, CHRM1, PFN1 | THRB 4867/4885ALDH1A1 2853/4885KDM4E 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.