Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | TDO2 | P48775 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801785 | 0.81 | TDO2 (0.52) | NPC1TDO2RAB9APDE10ASMN1; SMN2 | |
| SCHEMBL4165094 | 0.79 | SMN1; SMN2 (0.68) | NPC1TDO2RAB9APDE10ASMN1; SMN2 | |
| SCHEMBL8889339 | 0.79 | MCHR1 (0.57) | NPC1TDO2RAB9APDE10ASMN1; SMN2 | |
| SCHEMBL8889898 | 0.79 | NPC1 (0.55) | NPC1TDO2RAB9APDE10AKDM4E | |
| SCHEMBL14308364 | 0.76 | SMN1; SMN2 (0.59) | NPC1TDO2PDE10ASMN1; SMN2HPGD | |
| SCHEMBL19009922 | 0.76 | SMN1; SMN2 (0.59) | NPC1TDO2RAB9APDE10ASMN1; SMN2 | |
| SCHEMBL25228023 | 0.75 | TDO2 (0.55) | NPC1TDO2RAB9ASMN1; SMN2HPGD | |
| SCHEMBL11395164 | 0.74 | PDE10A (0.67) | NPC1RAB9APDE10ASMN1; SMN2HPGD | |
| SCHEMBL4698397 | 0.73 | NPC1 (0.74) | NPC1TDO2RAB9APDE10ASMN1; SMN2 | |
| SCHEMBL4702517 | 0.73 | NPC1 (0.80) | NPC1RAB9ASMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10581022-B2 | Polymerizable liquid crystal compound, composition, liquid crystal polymerization film-kind thereof and use thereof | JNC CORPORATION (JP) | 2020-03-03 | — | — | US | disclosed |
| US-20170174992-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, COMPOSITION, LIQUID CRYSTAL POLYMERIZATION FILM-KIND THEREOF AND USE THEREOF | JNC CORPORATION (JP) | 2017-06-22 | — | — | US | disclosed |
| US-20170174992-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, COMPOSITION, LIQUID CRYSTAL POLYMERIZATION FILM-KIND THEREOF AND USE THEREOF | JNC CORPORATION (JP) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10581022-B2 | Polymerizable liquid crystal compound, composition, liquid crystal polymerization film-kind thereof and use thereof | RCC1, CHRM1, PFN1 | NPC1 2240/4885TDO2 1130/4885RAB9A 1629/4885 |
| US-20170174992-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, COMPOSITION, LIQUID CRYSTAL POLYMERIZATION FILM-KIND THEREOF AND USE THEREOF | RCC1, CHRM1, PFN1 | NPC1 2240/4885TDO2 1130/4885RAB9A 1629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.