SCHEMBL1901012

SCHEMBL1901012

O=C(O)C(=CC=Cc1ccccc1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 2/20 0.60
LMNA P02545 7/20 0.50
MAPT P10636 4/20 0.50
MAOB P27338 2/20 0.50
PLIN1 O60240 2/20 0.50
RECQL P46063 2/20 0.50
PLIN5 Q00G26 2/20 0.50
ABHD5 Q8WTS1 2/20 0.50
BCHE P06276 1/20 0.50
TNFRSF1A P19438 1/20 0.50
ACHE P22303 1/20 0.50
CYP1B1 Q16678 1/20 0.50
GRIK1 P39086 1/20 0.47
MCL1 Q07820 1/20 0.47
PLA2G7 Q13093 1/20 0.47
ALDH1A1 P00352 6/20 0.47
MAPK1 P28482 2/20 0.47
TRPA1 O75762 1/20 0.47
ALOX5 P09917 1/20 0.47
HDAC3 O15379 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4817475 1.00 AKR1C1 (0.60) AKR1C1LMNAMAPTMAOBPLIN1
SCHEMBL11290831 0.87 TTR (0.50) AKR1C1LMNAMAPTMAOBPLIN1
SCHEMBL11290828 0.87 TTR (0.50) AKR1C1LMNAMAPTMAOBPLIN1
SCHEMBL11290833 0.87 TTR (0.50) AKR1C1LMNAMAPTMAOBPLIN1
SCHEMBL3218657 0.85 LMNA (0.47) AKR1C1LMNAMAPTMAOBPLIN1
SCHEMBL27746174 0.84 CYP1A1 (0.52) AKR1C1MAOBCYP1B1TRPA1HDAC3
SCHEMBL28205425 0.82 LCK (0.44) AKR1C1LMNAMAPTMAOBPLIN1
SCHEMBL14311430 0.82 AKR1C1 (0.45) AKR1C1MAOBGRIK1MCL1ALDH1A1
SCHEMBL5081017 0.81 ALDH1A1 (0.71) LMNAMAPTMAOBBCHECYP1B1
SCHEMBL4364435 0.78 AKR1C1 (0.52) AKR1C1MAPTRECQLALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1847884-B1 Electrophotographic developer and carrier therefor, core material particle for carrier for electrophotographic developer and production method thereof and image forming method RICOH CO LTD (JP) 2017-08-02 EP disclosed
US-8778587-B2 Carrier for electrostatic latent image developer, electrostatic latent image developer formed of carrier and toner, and process cartridge using the developer RICOH COMPANY, LTD. (JP) 2014-07-15 US disclosed
US-20130101930-A1 CARRIER FOR ELECTROSTATIC LATENT IMAGE DEVELOPER, ELECTROSTATIC LATENT IMAGE DEVELOPER FORMED OF CARRIER AND TONER, AND PROCESS CARTRIDGE USING THE DEVELOPER RICOH COMPANY, LTD. (JP) 2013-04-25 US disclosed
EP-2324934-B1 Carrier, developer using the carrier and process cartridge using the developer RICOH CO LTD (JP) 2013-04-24 EP disclosed
US-8039189-B2 Electrophotographic developer and carrier therefor, core material particle for carrier for electrophotographic developer and production method thereof and image forming method RICOH COMPANY, LTD. (JP) 2011-10-18 US disclosed
EP-1535670-B1 Vibrating sieve and method for classifying a particulate material RICOH CO LTD (JP) 2011-06-15 EP disclosed
EP-2324934-A1 Classifier and method of classifying and preparing a carrier, carrier and developer using the carrier, process cartridge using the developer Ricoh Company, Ltd. (JP) 2011-05-25 EP disclosed
US-7865114-B2 Image forming apparatus, image forming method and process cartridge RICOH COMPANY LIMITED (JP) 2011-01-04 US disclosed
US-7763410-B2 Electrophotographic developing carrier, associated apparatus and methodology of classification and application RICOH COMPANY, LTD. (JP) 2010-07-27 US disclosed
US-7468233-B2 Developer for use in electrophotography, image forming method and process cartridge RICOH COMPANY, LTD. (JP) 2008-12-23 US disclosed
EP-1260873-B1 Toner, developer and image forming method using the toner RICOH KK (JP) 2006-12-06 EP disclosed
US-20060057487-A1 Developer for use in electrophotography, image forming method and process cartridge RICOH COMPANY, LIMITED. (JP) 2006-03-16 US disclosed
US-20050170283-A1 Polymers based on cinnamic acid as a bottom antireflective coating for 157 NM photolithography POLARIS INNOVATIONS LIMITED (IE) 2005-08-04 US disclosed
US-20050158643-A1 Electrophotographic developing carrier, associated apparatus and methodology of classification and application RICOH COMPANY, LTD. (JP) 2005-07-21 US disclosed
EP-1535670-A2 Classifier and method of classifying and preparing a carrier, carrier and developer using the carrier, process cartridge using the developer Ricoh Company, Ltd. (JP) 2005-06-01 EP disclosed
US-20040265721-A1 Toner and method of preparing the toner RICOH COMPANY, LIMITED (JP) 2004-12-30 US disclosed
US-6835517-B2 Mixture of binder, colorant, charge control agent and wax; electrostatic latent images RICOH COMPANY, LTD. (JP) 2004-12-28 US disclosed
US-20030082472-A1 Toner, developer and image forming method using the toner RICOH COMPANY, LTD. (JP) 2003-05-01 US disclosed
EP-1260873-A1 Toner, developer and image forming method using the toner Ricoh Company (JP) 2002-11-27 EP disclosed
WO-1999029640-A2 COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR EISAI CO., LTD. (JP) 1999-06-17 WO disclosed