Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | BCHE | P06276 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | FOS | P01100 | 1/20 | 0.52 |
| ▸ | JUN | P05412 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29964493 | 0.82 | FOS (0.56) | ALDH1A1MEN1KMT2ABCHEMAOB | |
| SCHEMBL20424923 | 0.82 | FOS (0.56) | ALDH1A1MEN1KMT2ABCHEMAOB | |
| SCHEMBL4817475 | 0.81 | AKR1C1 (0.60) | ALDH1A1MEN1KMT2ABCHEMAOB | |
| SCHEMBL1901012 | 0.81 | AKR1C1 (0.60) | ALDH1A1MEN1KMT2ABCHEMAOB | |
| SCHEMBL5787713 | 0.78 | FOS (0.52) | ALDH1A1MEN1KMT2ABCHEMAOB | |
| SCHEMBL7592868 | 0.77 | RELA (0.70) | ALDH1A1MEN1KMT2ABCHEMAPT | |
| SCHEMBL7592867 | 0.77 | RELA (0.70) | ALDH1A1MEN1KMT2ABCHEMAPT | |
| SCHEMBL28577971 | 0.77 | KMT2A (0.83) | ALDH1A1MEN1KMT2ABCHEMAOB | |
| SCHEMBL8987299 | 0.77 | BCHE (1.00) | ALDH1A1MEN1KMT2ABCHEMAOB | |
| SCHEMBL8987297 | 0.77 | BCHE (1.00) | ALDH1A1MEN1KMT2ABCHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321044-B2 | Synthesis of oxygen-substituted benzocycloheptenes as valuable intermediate products for the production of tissue-selective estrogens | SCHERING AKTIENGESELLSCHAFT (DE) | 2008-01-22 | — | — | US | disclosed |
| US-7321044-B2 | Synthesis of oxygen-substituted benzocycloheptenes as valuable intermediate products for the production of tissue-selective estrogens | SCHERING AKTIENGESELLSCHAFT (DE) | 2008-01-22 | — | — | US | disclosed |
| EP-1436254-A1 | SYNTHESIS OF OXYGEN-SUBSTITUTED BENZOCYCLOHEPTENES, USED AS VALUABLE INTERMEDIATE PRODUCTS FOR PRODUCING TISSUE-SELECTIVE OESTROGENS | Schering Aktiengesellschaft (DE) | 2004-07-14 | — | — | EP | disclosed |
| US-20030162974-A1 | Synthesis of oxygen-substituted benzocycloheptenes as valuable intermediate products for the production of tissue-selective estrogens | SCHERING AG (DE) | 2003-08-28 | — | — | US | disclosed |
| WO-2003033461-A1 | SYNTHESIS OF OXYGEN-SUBSTITUTED BENZOCYCLOHEPTENES, USED AS VALUABLE INTERMEDIATE PRODUCTS FOR PRODUCING TISSUE-SELECTIVE OESTROGENS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162974-A1 | Synthesis of oxygen-substituted benzocycloheptenes as valuable intermediate products for the production of tissue-selective estrogens | CYP19A1, HSD17B11, SULT1E1 | ALDH1A1 243/4885MEN1 2672/4885KMT2A 2439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.