Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL1837276 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| SCHEMBL425147 | 0.90 | CYP3A4 (0.55) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| Propylene Glycol SCHEMBL8646897 | 0.90 | CYP3A4 (0.60) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| Glycerin SCHEMBL2587266 | 0.89 | ALDH1A1 (0.57) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| Glycerin SCHEMBL978611 | 0.89 | ALDH1A1 (0.57) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| Glycerin SCHEMBL4639031 | 0.89 | ALDH1A1 (0.57) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| Alcohol SCHEMBL2450700 | 0.88 | ALDH1A1 (0.60) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| Propylene Glycol SCHEMBL5072616 | 0.87 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| SCHEMBL13473918 | 0.87 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| SCHEMBL19462801 | 0.87 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153919-B | Enhanced steam extraction of bitumen from oil sands | 陶氏环球技术有限责任公司 | 2021-07-16 | — | — | CN | claimed |
| EP-2610271-B1 | Preparation of phthalate free ZN PP catalysts | BOREALIS AG (AT) | 2019-03-20 | — | — | EP | claimed |
| CN-109312234-A | Composition for steam extraction pitch | 陶氏环球技术有限责任公司 | 2019-02-05 | — | — | CN | claimed |
| CN-109153919-A | Strengthen steam extraction pitch from oil-sand | 陶氏环球技术有限责任公司 | 2019-01-04 | — | — | CN | claimed |
| US-20250282897-A1 | PROCESS FOR MAKING A SOLID CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION AND CO-POLYMERIZATION WITH HIGH ACTIVITY AND IMPROVED REACTOR OPERABILITY | FORMOSA PLASTICS CORP USA (US) | 2025-09-11 | — | — | US | disclosed |
| US-20250115687-A1 | PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS | FORMOSA PLASTICS CORP USA (US) | 2025-04-10 | — | — | US | disclosed |
| WO-2025075722-A1 | PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS | FORMOSA PLASTICS CORPORATION, U.S.A. (US) | 2025-04-10 | — | — | WO | disclosed |
| US-20230183395-A1 | PREPARATION OF PHTHALATE FREE ZN PP CATALYSTS | BOREALIS AG (AT) | 2023-06-15 | — | — | US | disclosed |
| EP-3837290-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2023-05-10 | — | — | EP | disclosed |
| CN-111556882-B | Polymer additives for reducing viscosity loss upon tinting | 巴斯夫欧洲公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-111278934-B | Aqueous silicone polymer emulsions | 巴斯夫欧洲公司 | 2022-04-12 | — | — | CN | disclosed |
| US-11220519-B2 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2022-01-11 | — | — | US | disclosed |
| US-20110117378-A1 | AQUEOUS COATING COMPOSITION AND METHOD FOR FORMING MULTILAYER COATING FILM | KANSAI PAINT CO., LTD. (JP) | 2011-05-19 | — | — | US | disclosed |
| US-7842751-B2 | Water-based paint compositions | KANSAI PAINT CO., LTD. (JP) | 2010-11-30 | — | — | US | disclosed |
| WO-2010007891-A1 | AQUEOUS COATING COMPOSITION AND METHOD FOR FORMING MULTILAYER COATING FILM | KANSAI PAINT CO., LTD. (JP) | 2010-01-21 | — | — | WO | disclosed |
| US-20090305050-A1 | Water-Based Paint Compositions | KANSAI PAINT CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090191419-A1 | WATER-BASED PAINT COMPOSITIONS | KANSAI PAINT CO., LTD. (JP) | 2009-07-30 | — | — | US | disclosed |
| CN-101495581-A | Aqueous coating composition | KANSAI PAINT CO LTD (JP) | 2009-07-29 | — | — | CN | disclosed |
| CN-101421367-A | Aqueous coating composition | KANSAI PAINT CO LTD (JP) | 2009-04-29 | — | — | CN | disclosed |
| EP-0334956-A1 | HEMOLYSIS INHIBITOR AND MEDICAL RESIN COMPOSITION, MEDICAL IMPLEMENT, AND BLOOD-PRESERVING FLUID CONTAINING THE SAME | Kao Corporation (JP) | 1989-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11220519-B2 | Components and catalysts for the polymerization of olefins | COG4, SCO2, COG2 | ALDH1A1 3106/4885CYP3A4 82/4885TSHR 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.