SCHEMBL1901148

SCHEMBL1901148

Cc1ccc(-c2ccccc2-c2cc(N)cc(N)c2-c2ccc(C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
NPC1 O15118 4/20 0.41
ADORA2A P29274 2/20 0.35
ADORA1 P30542 1/20 0.35
ACHE P22303 1/20 0.34
ALDH1A1 P00352 4/20 0.34
HSD17B10 Q99714 1/20 0.34
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
KDM4E B2RXH2 3/20 0.34
POLB P06746 2/20 0.34
PPARG P37231 2/20 0.34
MCL1 Q07820 1/20 0.34
NR2E3 Q9Y5X4 1/20 0.34
NCOR2 Q9Y618 1/20 0.34
HPGD P15428 3/20 0.33
PTPRC P08575 2/20 0.33
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2336893 0.80 ACHE (0.48) RAB9AMEN1KMT2ANPC1ACHE
SCHEMBL15290875 0.78 ACHE (0.59) RAB9AMEN1KMT2ANPC1ADORA2A
SCHEMBL2011278 0.77 PTPRC (0.53) RAB9AMEN1KMT2ANPC1ACHE
SCHEMBL25135347 0.76 HSD17B10 (0.48) MEN1KMT2AADORA2AALDH1A1HSD17B10
SCHEMBL27575461 0.76 ALDH1A1 (0.56) RAB9AMEN1KMT2ANPC1ADORA2A
SCHEMBL6014197 0.76 ACHE (0.62) RAB9AMEN1KMT2ANPC1ADORA2A
SCHEMBL20530969 0.75 HSD17B10 (0.46) RAB9AMEN1KMT2ANPC1ALDH1A1
SCHEMBL4843094 0.74 ADORA2A (0.50) RAB9AMEN1KMT2ANPC1ADORA2A
SCHEMBL8036362 0.73 LMNA (0.50) RAB9AMEN1KMT2ANPC1ACHE
SCHEMBL394565 0.72 ALDH1A1 (0.65) RAB9AMEN1KMT2ANPC1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011055932-A9 ORGANIC COMPOUND, ORGANIC ELECTRONIC DEVICE USING SAME, AND TERMINAL FOR SAME 덕산하이메탈(주) (KR) 2011-09-01 WO disclosed
WO-2011055932-A2 ORGANIC COMPOUND, ORGANIC ELECTRONIC DEVICE USING SAME, AND TERMINAL FOR SAME 덕산하이메탈(주) (KR) 2011-05-12 WO disclosed