SCHEMBL2336893

SCHEMBL2336893

Cc1ccc(-c2c(N)cc(N)cc2N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.48
ALDH1A1 P00352 7/20 0.43
TSHR P16473 4/20 0.43
TDP1 Q9NUW8 5/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
CYP3A4 P08684 2/20 0.42
ALOX15 P16050 2/20 0.42
TP53 P04637 2/20 0.42
THRB P10828 1/20 0.42
CASP1 P29466 1/20 0.41
HEXA P06865 1/20 0.39
HEXB P07686 1/20 0.39
HSD17B10 Q99714 3/20 0.39
KDM4E B2RXH2 2/20 0.39
MEN1 O00255 1/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
UBE2N P61088 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29281942 0.85 ALDH1A1 (0.55) ACHEALDH1A1TSHRTDP1SMN1; SMN2
SCHEMBL1901148 0.80 RAB9A (0.41) ACHEALDH1A1SMN1; SMN2HSD17B10KDM4E
SCHEMBL27458150 0.78 CYP3A4 (0.48) ACHEALDH1A1TSHRTDP1SMN1; SMN2
SCHEMBL4248242 0.77 TDP1 (0.48) ACHEALDH1A1TSHRTDP1SMN1; SMN2
SCHEMBL24254914 0.76 HSD17B10 (0.56) ALDH1A1TSHRTDP1SMN1; SMN2CYP3A4
SCHEMBL28153334 0.75 MAOA (0.48) ACHEALDH1A1TSHRTDP1SMN1; SMN2
SCHEMBL21922962 0.75 ACHE (0.52) ACHEALDH1A1TSHRTDP1SMN1; SMN2
SCHEMBL615165 0.74 ACHE (0.50) ACHEALDH1A1TSHRTDP1SMN1; SMN2
SCHEMBL27735148 0.73 HRH3 (0.54)
SCHEMBL6011415 0.73 ACHE (0.50) ACHEALDH1A1TSHRTDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111662314-B Polycyclic aromatic compound or condensation polymer thereof, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2021-10-26 CN disclosed
CN-109155368-B Organic electroluminescent element, display device and lighting device 学校法人关西学院 2021-04-06 CN disclosed
CN-106905367-B Electron transport material or electron injection material, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-17 CN disclosed
CN-111909189-A Polycyclic aromatic compound, multimer thereof, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-10 CN disclosed
CN-111892615-A Polycyclic aromatic compound, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-06 CN disclosed
CN-107851724-B Organic electroluminescent element, display device and lighting device 学校法人关西学院 2020-10-09 CN disclosed
CN-105431439-B Polycyclic aromatic compound, method for producing same, material for organic device, and application thereof 学校法人关西学院 2020-09-25 CN disclosed
CN-111662314-A Polycyclic aromatic compound or condensation polymer thereof, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-09-15 CN disclosed
US-20200091431-A1 ORGANIC ELECTROLUMINESCENT ELEMENT KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-03-19 US disclosed
US-20180301629-A1 ORGANIC ELECTROLUMINESCENT ELEMENT KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-10-18 US disclosed
EP-1126788-B1 SYSTEM FOR RADIOGRAPHIC IMAGING OF TISSUE VERITAS PHARMACEUTICALS (US) 2011-08-24 EP disclosed
US-6923950-B2 System and method for radiographic imaging of tissue VERITAS PHARMACEUTICALS, INC. (US) 2005-08-02 US disclosed
US-20030091508-A1 System and method for radiographic imaging of tissue VERITAS PHARMACEUTICALS, INC. 2003-05-15 US disclosed
EP-1126788-A2 SYSTEM AND METHOD FOR RADIOGRAPHIC IMAGING OF TISSUE Veritas Pharmaceuticals (US) 2001-08-29 EP disclosed
US-20010001011-A1 System and method for radiographic imaging of tissue SALB JESSE (US) 2001-05-10 US disclosed
US-6226352-B1 System and method for radiographic imaging of tissue VERITAS PHARMACEUTICALS, INC. 2001-05-01 US disclosed
WO-2000013590-A2 SYSTEM AND METHOD FOR RADIOGRAPHIC IMAGING OF TISSUE VERITAS PHARMACEUTICALS (US) 2000-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200091431-A1 ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, EPB41L2, EPB41 ACHE 2979/4885ALDH1A1 1008/4885TSHR 4003/4885
US-20010001011-A1 System and method for radiographic imaging of tissue HK1, HK2, SLC2A8 ACHE 1525/4885ALDH1A1 2627/4885TSHR 781/4885
US-20030091508-A1 System and method for radiographic imaging of tissue HK1, HK2, SLC2A8 ACHE 1525/4885ALDH1A1 2627/4885TSHR 781/4885
US-20180301629-A1 ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, EPB41L2, EPB41 ACHE 2979/4885ALDH1A1 1008/4885TSHR 4003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.