Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3472112 | 0.82 | SYK (0.43) | SYKGAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL24787 | 0.80 | CA1 (0.32) | KDM4EALDH1A1HPGDMAOBCA12 | |
| SCHEMBL6574222 | 0.79 | MAOB (0.53) | ALDH1A1MAOBCA12CA1CA2 | |
| SCHEMBL5202843 | 0.77 | LTA4H (0.47) | SYKCA12CA2CA9 | |
| SCHEMBL481286 | 0.77 | CA12 (0.50) | GAASMN1; SMN2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1785520 | 0.77 | MAOB (0.43) | SYKGAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL187687 | 0.77 | ALDH3A1 (0.50) | SYKKDM4EALDH1A1L3MBTL1MAOB | |
| SCHEMBL3357599 | 0.77 | ALDH1A1 (0.46) | SYKGAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4652388 | 0.77 | APP (0.50) | SYKGAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2061077 | 0.77 | TDP1 (0.52) | SYKGAASMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3009433-B1 | 2-PHENYL-1,3-OXAZOLE AND 5-PHENYL-1,2,4-OXADIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | DAIICHI SANKYO CO LTD (JP) | 2017-06-21 | — | — | EP | disclosed |