Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28143455 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28724810 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8059663 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL711064 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1331961 | 0.94 | — | — | |
| Bicarbonate SCHEMBL60565 | 0.94 | — | — | |
| Bicarbonate SCHEMBL532723 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3261 | 0.94 | — | — | |
| Bicarbonate SCHEMBL9145494 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3266233 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108504157-A | A kind of fire-proof and thermal-insulation paint | 南通森德诺家纺科技有限公司 | 2018-09-07 | — | — | CN | claimed |
| CN-104559379-A | Conductive heating coating | JIANG YUNHUA | 2015-04-29 | — | — | CN | claimed |
| JP-60238341-A | — | — | None | — | — | JP | disclosed |
| EP-4466247-A1 | METHOD FOR PRODUCING HESPERETIN DIHYDROCHALCONE | Symrise AG (DE) | 2024-11-27 | — | — | EP | disclosed |
| US-20240376035-A1 | METHOD FOR PRODUCING HESPERETIN DIHYDROCHALCONE | SYMRISE AG (DE) | 2024-11-14 | — | — | US | disclosed |
| CN-118632829-A | Process for preparing hesperetin dihydrochalcone | 西姆莱斯有限公司 | 2024-09-10 | — | — | CN | disclosed |
| US-20240132632-A1 | HYDROGENATED POLYMER COMPOSITION CONTAINING HYDROGENATED CONJUGATED DIENE MODIFIED POLYMER HAVING BORON-CONTAINING FUNCTIONAL GROUP AND METHOD FOR PRODUCING SAME | KURARAY CO., LTD. (JP) | 2024-04-25 | — | — | US | disclosed |
| EP-4293050-A1 | HYDROGENATED POLYMER COMPOSITION CONTAINING HYDROGENATED CONJUGATED-DIENE MODIFIED POLYMER HAVING BORON-CONTAINING FUNCTIONAL GROUP, AND METHOD FOR PRODUCING SAME | Kuraray Co., Ltd. (JP) | 2023-12-20 | — | — | EP | disclosed |
| CN-116888160-A | Hydrogenated polymer composition comprising hydrogenated conjugated diene modified polymer having boron-containing functional group and method for producing same | 株式会社可乐丽 | 2023-10-13 | — | — | CN | disclosed |
| WO-2023138777-A1 | METHOD FOR PRODUCING HESPERETIN DIHYDROCHALCONE | SYMRISE AG (DE) | 2023-07-27 | — | — | WO | disclosed |
| WO-2023139225-A1 | METHOD FOR PRODUCING HESPERETIN DIHYDROCHALCONE | SYMRISE AG (DE) | 2023-07-27 | — | — | WO | disclosed |
| WO-2021132286-A1 | HYDROGENATED CONJUGATED DIENE GRAFT POLYMER AND METHOD FOR PRODUCING SAME | 株式会社クラレ | 2021-07-01 | — | — | WO | disclosed |
| WO-2021132285-A1 | OIL COMPOSITION AND VISCOSITY INDEX IMPROVER COMPRISING CONJUGATED DIENE-BASED GRAFT POLYMER | 株式会社クラレ | 2021-07-01 | — | — | WO | disclosed |
| CN-104559379-A | Conductive heating coating | JIANG YUNHUA | 2015-04-29 | — | — | CN | disclosed |
| EP-2264078-B1 | HYDROGENATED BETA-PINENE-BASED POLYMER AND MOLDED ARTICLE COMPRISING THE SAME | KURARAY CO (JP) | 2015-03-04 | — | — | EP | disclosed |
| CN-101990549-B | Hydrogenated beta-pinene-based polymer and molded article comprising the same | KURARAY CO | 2014-08-20 | — | — | CN | disclosed |
| US-8497327-B2 | Hydrogenated β-pinene-based polymers and molded articles comprising the same | KURARAY CO., LTD. (JP) | 2013-07-30 | — | — | US | disclosed |
| US-20110124830-A1 | HYDROGENATED BETA-PINENE-BASED POLYMERS AND MOLDED ARTICLES COMPRISING THE SAME | KURARAY CO., LTD. (JP) | 2011-05-26 | — | — | US | disclosed |
| EP-2264078-A1 | HYDROGENATED BETA-PINENE-BASED POLYMER AND MOLDED ARTICLE COMPRISING THE SAME | Kuraray Co., Ltd. (JP) | 2010-12-22 | — | — | EP | disclosed |
| JP-S60238341-A | POLYPROPYLENE RESIN COMPOSITION | IDEMITSU PETROCHEM CO LTD | 1985-11-27 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376035-A1 | METHOD FOR PRODUCING HESPERETIN DIHYDROCHALCONE | DHPS, HES1, NISCH | CA4 2312/4885CA1 2788/4885FAHD1 3617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.