Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | HPD | P32754 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | USP14 | P54578 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902028 | 0.91 | GRM5 (0.45) | GRM5EGLN2GLA | |
| SCHEMBL1904865 | 0.86 | EGLN2 (0.34) | GRM5EGLN2GLAKDM1AHPD | |
| SCHEMBL1076165 | 0.81 | POLB (0.36) | GRM5EGLN2 | |
| SCHEMBL1908385 | 0.80 | EGLN2 (0.34) | GRM5EGLN2KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL1900602 | 0.78 | TDP2 (0.42) | GRM5EGLN2ALDH1A1 | |
| SCHEMBL1904366 | 0.76 | ALDH1A1 (0.35) | GRM5EGLN2KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL19967260 | 0.74 | HTT (0.41) | GRM5ALDH1A1 | |
| SCHEMBL1074771 | 0.69 | POLB (0.39) | GRM5ALDH1A1 | |
| SCHEMBL1900183 | 0.68 | KDM4E (0.35) | GRM5EGLN2 | |
| SCHEMBL18707647 | 0.68 | NOTUM (0.39) | GLAHPDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056463-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |