Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 14/20 | 0.58 |
| ▸ | CASP7 | P55210 | 10/20 | 0.58 |
| ▸ | CASP9 | P55211 | 3/20 | 0.58 |
| ▸ | CASP1 | P29466 | 3/20 | 0.58 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.43 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7886597 | 0.91 | CASP3 (0.69) | CASP3CASP7CASP9CASP1ADAMTS4 | |
| SCHEMBL18471652 | 0.91 | CASP3 (0.69) | CASP3CASP7CASP9CASP1ADAMTS4 | |
| SCHEMBL7890390 | 0.81 | ADAMTS4 (0.57) | CASP3CASP7CASP9CASP1ADAMTS4 | |
| SCHEMBL18473182 | 0.81 | ADAMTS4 (0.57) | CASP3CASP7CASP9CASP1ADAMTS4 | |
| SCHEMBL18472733 | 0.81 | CASP3 (0.59) | CASP3CASP7CASP9CASP1ADAMTS4 | |
| SCHEMBL7880525 | 0.81 | CASP3 (0.59) | CASP3CASP7CASP9CASP1ADAMTS4 | |
| SCHEMBL18782168 | 0.80 | CASP3 (0.48) | CASP3CASP7CASP9CASP1ADAMTS4 | |
| SCHEMBL19015952 | 0.79 | PSMB8 (0.39) | CASP3CASP7CASP9CASP1ADAMTS4 | |
| SCHEMBL7887004 | 0.78 | CASP3 (0.53) | CASP3CASP7CASP9CASP1ADAMTS4 | |
| SCHEMBL7966457 | 0.76 | ADAMTS4 (0.47) | CASP3CASP7CASP9CASP1ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |