Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 15/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 11/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP9 | P55211 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7886070 | 0.91 | CASP3 (0.46) | PSMB8PSMB5CASP3CASP1CASP7 | |
| SCHEMBL7887004 | 0.81 | CASP3 (0.53) | PSMB8PSMB5CASP3CASP1CASP7 | |
| SCHEMBL18472733 | 0.80 | CASP3 (0.59) | PSMB8PSMB5CASP3CASP1CASP7 | |
| SCHEMBL7880525 | 0.80 | CASP3 (0.59) | PSMB8PSMB5CASP3CASP1CASP7 | |
| SCHEMBL19015805 | 0.79 | CASP3 (0.58) | CASP3CASP1CASP7CASP9ADAMTS4 | |
| SCHEMBL19015891 | 0.75 | NPY5R (0.41) | PSMB8PSMB5ADAMTS4NPY5R | |
| SCHEMBL19015948 | 0.75 | NPY5R (0.49) | PSMB8PSMB5ADAMTS4NPY5R | |
| SCHEMBL19015900 | 0.72 | CASP3 (0.51) | PSMB8PSMB5CASP3CASP1CASP7 | |
| SCHEMBL18782302 | 0.71 | CASP3 (0.45) | CASP3CASP1CASP7CASP9ADAMTS4 | |
| SCHEMBL18782015 | 0.70 | CASP3 (0.66) | PSMB5CASP3CASP1CASP7CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |