Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 8/20 | 0.53 |
| ▸ | CASP7 | P55210 | 6/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | CASP9 | P55211 | 2/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 7/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7886070 | 0.90 | CASP3 (0.46) | CASP3CASP7CASP1CASP9PSMB8 | |
| SCHEMBL18471652 | 0.87 | CASP3 (0.69) | CASP3CASP7CASP1CASP9ADAMTS4 | |
| SCHEMBL7886597 | 0.87 | CASP3 (0.69) | CASP3CASP7CASP1CASP9ADAMTS4 | |
| SCHEMBL19015948 | 0.83 | NPY5R (0.49) | PSMB8PSMB5NPY5RADAMTS4GFER | |
| SCHEMBL19015952 | 0.81 | PSMB8 (0.39) | CASP3CASP7CASP1CASP9PSMB8 | |
| SCHEMBL19015805 | 0.78 | CASP3 (0.58) | CASP3CASP7CASP1CASP9ADAMTS4 | |
| SCHEMBL18472733 | 0.78 | CASP3 (0.59) | CASP3CASP7CASP1CASP9PSMB8 | |
| SCHEMBL7880525 | 0.78 | CASP3 (0.59) | CASP3CASP7CASP1CASP9PSMB8 | |
| SCHEMBL7879499 | 0.76 | TDP1 (0.55) | ADAMTS4GFER | |
| SCHEMBL19015891 | 0.75 | NPY5R (0.41) | PSMB8PSMB5NPY5RADAMTS4GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133000-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES INC. (CA) | 2010-11-25 | — | — | WO | disclosed |