Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 8/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSH | P09668 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358268 | 0.91 | CASP3 (0.52) | CASP3CTSLCASP7CTSBCTSH | |
| SCHEMBL7358261 | 0.91 | CASP3 (0.52) | CASP3CTSLCASP7CTSBCTSH | |
| SCHEMBL7358274 | 0.91 | CASP3 (0.52) | CASP3CTSLCASP7CTSBCTSH | |
| SCHEMBL19015816 | 0.90 | CASP3 (0.51) | CASP3CTSLCASP7CTSBCTSH | |
| SCHEMBL7214816 | 0.81 | CASP3 (0.51) | CASP3CTSLCASP7CTSBCTSH | |
| SCHEMBL18782008 | 0.81 | CTSK (0.47) | CASP3CTSLCTSBCTSHCTSS | |
| SCHEMBL19015928 | 0.81 | ABCB1 (0.40) | CASP3CTSLCTSBCTSHCTSS | |
| SCHEMBL7887287 | 0.77 | CTSB (0.42) | CASP3CTSLCTSBCTSHCTSS | |
| SCHEMBL19015802 | 0.77 | CTSB (0.42) | CASP3CTSLCTSBCTSHCTSS | |
| SCHEMBL19015933 | 0.76 | ABCB1 (0.44) | CASP3CTSLCASP7CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |