Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 14/20 | 0.46 |
| ▸ | CASP7 | P55210 | 8/20 | 0.46 |
| ▸ | CASP1 | P29466 | 6/20 | 0.46 |
| ▸ | CASP9 | P55211 | 5/20 | 0.46 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.46 |
| ▸ | CASP4 | P49662 | 4/20 | 0.42 |
| ▸ | CASP5 | P51878 | 3/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.42 |
| ▸ | CASP10 | Q92851 | 3/20 | 0.42 |
| ▸ | CASP6 | P55212 | 2/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 2/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015945 | 0.94 | CASP3 (0.49) | CASP3CASP7CASP1CASP9TASP1 | |
| SCHEMBL19015826 | 0.77 | PSMB5 (0.36) | CASP3CASP7CASP1CASP9TASP1 | |
| SCHEMBL18471954 | 0.77 | CASP3 (0.69) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL19944475 | 0.76 | CASP3 (0.44) | CASP3CASP7CASP1CASP9CTSC | |
| SCHEMBL19015757 | 0.74 | BMP1 (0.36) | CASP3CASP7CASP1CASP9BMP1 | |
| SCHEMBL19015752 | 0.74 | CASP3 (0.79) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL19944566 | 0.72 | CASP3 (0.72) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL97580 | 0.72 | GLO1 (0.40) | BMP1 | |
| SCHEMBL9800725 | 0.70 | MME (0.42) | — | |
| SCHEMBL15459254 | 0.69 | CTSC (0.63) | CASP3CASP7CASP1CASP9TASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |