Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015919 | 0.78 | CASP3 (0.39) | SMN1; SMN2 | |
| SCHEMBL19015826 | 0.77 | PSMB5 (0.36) | — | |
| SCHEMBL19015751 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2CTSKTDP1 | |
| SCHEMBL19944842 | 0.75 | SMN1; SMN2 (0.38) | SMN1; SMN2CTSSCTSK | |
| SCHEMBL19944837 | 0.73 | PSMB5 (0.46) | CTSSCTSK | |
| SCHEMBL24235745 | 0.72 | KMT2A (0.40) | CTSKTDP1 | |
| SCHEMBL13471019 | 0.72 | CASP3 (0.46) | CTSS | |
| SCHEMBL5017558 | 0.72 | L3MBTL1 (0.37) | SMN1; SMN2CTSKTDP1 | |
| SCHEMBL24235667 | 0.72 | L3MBTL1 (0.37) | SMN1; SMN2CTSKTDP1 | |
| SCHEMBL5017556 | 0.72 | L3MBTL1 (0.37) | SMN1; SMN2CTSKTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |