Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966457 | 0.85 | ADAMTS4 (0.47) | NPY5RADAMTS4GFERKDM4ESMN1; SMN2 | |
| SCHEMBL19015948 | 0.85 | NPY5R (0.49) | NPY5RADAMTS4GFERKDM4EPSMB8 | |
| SCHEMBL7879499 | 0.79 | TDP1 (0.55) | ADAMTS4GFERKDM4EALDH1A1MMP13 | |
| SCHEMBL19015812 | 0.78 | CYP1A2 (0.40) | KDM4EALDH1A1HSD17B10NPSR1CYSLTR1 | |
| SCHEMBL7886070 | 0.76 | CASP3 (0.46) | NPY5RADAMTS4PSMB8PSMB5 | |
| SCHEMBL7890390 | 0.75 | ADAMTS4 (0.57) | NPY5RADAMTS4GFERKDM4EMMP13 | |
| SCHEMBL18473182 | 0.75 | ADAMTS4 (0.57) | NPY5RADAMTS4GFERKDM4EMMP13 | |
| SCHEMBL7887004 | 0.75 | CASP3 (0.53) | NPY5RADAMTS4GFERPSMB8PSMB5 | |
| SCHEMBL19015952 | 0.75 | PSMB8 (0.39) | NPY5RADAMTS4PSMB8PSMB5 | |
| SCHEMBL19015759 | 0.74 | CASP3 (0.51) | CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |