Sugi Predict

Sugi Predict / Compounds / SCHEMBL190209

SCHEMBL190209

SCHEMBL190209

Nc1cc(N)cc(B(O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 5/20 0.56
▸ ALDH1A1 P00352 2/20 0.56
▸ KDM4E B2RXH2 1/20 0.56
▸ CA4 P22748 1/20 0.36
▸ CA6 P23280 1/20 0.36
▸ CA5A P35218 1/20 0.36
▸ CA7 P43166 1/20 0.36
▸ CA14 Q9ULX7 1/20 0.36
▸ CA5B Q9Y2D0 1/20 0.36
▸ CA2 P00918 3/20 0.33
▸ CA1 P00915 2/20 0.33
▸ TSHR P16473 2/20 0.33
▸ CYP3A4 P08684 2/20 0.33
▸ F11 P03951 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ LPL P06858 1/20 0.33
▸ LIPG Q9Y5X9 1/20 0.33
▸ CASP1 P29466 1/20 0.33
▸ RECQL P46063 1/20 0.33
▸ MGLL Q99685 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3789580 0.84 ENPP2 (0.48) ENPP2ALDH1A1KDM4ECA4CA6
SCHEMBL3790128 0.82 KDM4E (0.46) ENPP2ALDH1A1KDM4E
SCHEMBL25651924 0.82 CYP3A4 (0.55) ENPP2ALDH1A1KDM4ETSHRCYP3A4
SCHEMBL1289919 0.82 KDM4E (0.46) ENPP2ALDH1A1KDM4ECA1
SCHEMBL3786835 0.82 ALDH1A1 (0.57) ENPP2ALDH1A1KDM4ECA2TSHR
SCHEMBL24661957 0.82 ALDH1A1 (0.46) ENPP2ALDH1A1KDM4ECA2CA1
SCHEMBL30006611 0.82 KDM4E (0.46) ENPP2ALDH1A1KDM4ECA1
SCHEMBL3784998 0.78 ENPP2 (0.50) ENPP2ALDH1A1KDM4EF11LPL
SCHEMBL3782234 0.77 KDM4E (0.42) ENPP2ALDH1A1KDM4E
SCHEMBL16899205 0.77 ALDH1A1 (0.42) ENPP2ALDH1A1KDM4ECA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122012973-A High-strength hard alloy and preparation method thereof 成都工业职业技术学院 2026-05-12 — — CN claimed
CN-118978766-A Flame-retardant synthetic plastic and preparation method thereof 临沂三鑫塑料包装制品有限公司 2024-11-19 — — CN claimed
CN-122012973-A High-strength hard alloy and preparation method thereof 成都工业职业技术学院 2026-05-12 — — CN disclosed
CN-120967570-A Wear-resistant scratch-resistant textile fabric and preparation method thereof 南通科晟纺织有限公司 2025-11-18 — — CN disclosed
CN-118978766-A Flame-retardant synthetic plastic and preparation method thereof 临沂三鑫塑料包装制品有限公司 2024-11-19 — — CN disclosed
CN-118448806-A Functional aramid nanofiber coated diaphragm and preparation method and application thereof 华中科技大学 2024-08-06 — — CN disclosed
EP-3490970-B1 COMPOSITIONS FOR THE TREATMENT OF PULMONARY FIBROSIS VECTUS BIOSYSTEMS LTD (AU) 2023-09-13 — — EP disclosed
EP-3490970-B1 COMPOSITIONS FOR THE TREATMENT OF PULMONARY FIBROSIS VECTUS BIOSYSTEMS LTD (AU) 2023-09-13 — — EP disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 — — US disclosed
US-11401245-B2 Compositions for the treatment of pulmonary fibrosis VECTUS BIOSYSTEMS LIMITED (AU) 2022-08-02 — — US disclosed
US-20210130301-A1 COMPOSITIONS FOR THE TREATMENT OF PULMONARY FIBROSIS VECTUS BIOSYSTEMS LIMITED (AU) 2021-05-06 — — US disclosed
WO-2018018091-A1 COMPOSITIONS FOR THE TREATMENT OF PULMONARY FIBROSIS VECTUS BIOSYSTEMS LIMITED (AU) 2018-02-01 — — WO disclosed
US-20160152632-A9 PHARMACEUTICAL COMPOUNDS PIRAMED LIMITED (GB) 2016-06-02 — — US disclosed
US-20140309216-A1 PHARMACEUTICAL COMPOUNDS HOFFMANN LA ROCHE (CH) 2014-10-16 — — US disclosed
US-8802670-B2 Pharmaceutical compounds F. HOFFMANN-LA ROCHE AG (CH) 2014-08-12 — — US disclosed
EP-2402347-A1 Pharmaceutical compounds F. Hoffmann-La Roche AG (CH) 2012-01-04 — — EP disclosed
EP-2041139-B1 PHARMACEUTICAL COMPOUNDS HOFFMANN LA ROCHE (CH) 2011-11-09 — — EP disclosed
EP-2041139-A2 PHARMACEUTICAL COMPOUNDS F.HOFFMANN-LA ROCHE AG (CH) 2009-04-01 — — EP disclosed
US-20080076758-A1 1S,4S)-2-((2-(1H-indazol-4-yl)-4- morpholinothieno[3,2-d]pyrirnidin-6- yl)methyl)-5-methylsulfonyl-2,5- diaza-bicyclo[2.2.1]heptane; 2-(6-fluoropyridin-3-yl)-6-((4- methylsulfonylpiperazin-1-yl)methyl)-4- morpholinothieno[3,2-d]pyrimidine; treats cancer mediated by pik3 kinase; enzyme inhibitors PIRAMED LIMITED (GB) 2008-03-27 — — US disclosed
WO-2007127175-A2 PHARMACEUTICAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2007-11-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11401245-B2 Compositions for the treatment of pulmonary fibrosis ELANE, MMP1, CCL11 ENPP2 53/4885ALDH1A1 1395/4885KDM4E 3994/4885
US-20080076758-A1 1S,4S)-2-((2-(1H-indazol-4-yl)-4- morpholinothieno[3,2-d]pyrirnidin-6- yl)methyl)-5-methylsulfonyl-2,5- diaza-bicyclo[2.2.1]heptane; 2-(6-fluoropyridin-3-yl)-6-((4- methylsulfonylpiperazin-1-yl)methyl)-4- morpholinothieno[3,2-d]pyrimidine; treats cancer mediated by pik3 kinase; enzyme inhibitors PIK3CA, PIK3CD, PIK3CB ENPP2 1543/4885ALDH1A1 2268/4885KDM4E 529/4885
US-20140309216-A1 PHARMACEUTICAL COMPOUNDS PIK3CA, PIK3CD, AKT3 ENPP2 782/4885ALDH1A1 1974/4885KDM4E 3726/4885
US-20210130301-A1 COMPOSITIONS FOR THE TREATMENT OF PULMONARY FIBROSIS ELANE, MMP1, CCL11 ENPP2 53/4885ALDH1A1 1395/4885KDM4E 3994/4885
US-20160152632-A9 PHARMACEUTICAL COMPOUNDS PIK3CA, PIK3CD, AKT3 ENPP2 782/4885ALDH1A1 1974/4885KDM4E 3726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.