Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 12/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 5/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744422 | 0.81 | BCHE (0.50) | GNAI3GNAO1GNAI1BCHE | |
| SCHEMBL19010275 | 0.80 | SSTR4 (0.35) | SSTR4SSTR1HTR1F | |
| SCHEMBL23894245 | 0.79 | SSTR4 (0.34) | SSTR4SSTR1HTR1F | |
| SCHEMBL8744430 | 0.77 | GNAI3 (0.43) | SSTR4GNAI3GNAO1GNAI1BCHE | |
| SCHEMBL19000028 | 0.76 | SIGMAR1 (0.45) | KMT2ASSTR4HTR1F | |
| SCHEMBL15721227 | 0.74 | CHRM3 (0.38) | KMT2ASSTR4GNAI3GNAO1GNAI1 | |
| SCHEMBL18979956 | 0.72 | GAA (0.37) | SSTR4GNAI3GNAO1GNAI1 | |
| SCHEMBL29722328 | 0.72 | NCF1 (0.35) | KMT2ASSTR4GNAI3GNAO1GNAI1 | |
| SCHEMBL12719407 | 0.71 | BCHE (0.49) | KMT2AGNAI3GNAO1GNAI1BCHE | |
| SCHEMBL8744405 | 0.70 | GNAO1 (0.48) | GNAI3GNAO1GNAI1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106607-A1 | POLYCYCLIC TLR7/8 ANTAGONISTS AND USE THEREOF IN THE TREATMENT OF IMMUNE DISORDERS | MERCK PATENT GMBH (DE) | 2017-06-22 | — | — | WO | disclosed |