⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31008628 | 1.00 | — | — | |
| Bromobenzene SCHEMBL27584036 | 0.85 | ALDH1A1 (0.42) | — | |
| SCHEMBL27564101 | 0.81 | ACHE (0.45) | — | |
| Benzoic Acid SCHEMBL23501738 | 0.80 | GABRP (0.47) | — | |
| Ethoxycarbonyl Group SCHEMBL27820734 | 0.77 | NPC1 (0.37) | — | |
| SCHEMBL2174027 | 0.76 | — | — | |
| SCHEMBL416458 | 0.74 | — | — | |
| SCHEMBL24304970 | 0.72 | SCN9A (0.48) | — | |
| Diaminopyrimidine SCHEMBL53016 | 0.72 | — | — | |
| Diaminopyrimidine SCHEMBL6013998 | 0.72 | HSP90AA1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1638 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115380029-B | Compounds for the treatment of tuberculosis | 南洋理工大学 | 2025-06-17 | — | — | CN | claimed |
| CN-118125984-A | Benzenesulfonamide compound and preparation method and application thereof | 中国药科大学 | 2024-06-04 | — | — | CN | claimed |
| US-20230348436-A1 | COMPOUNDS FOR TREATING TUBERCULOSIS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2023-11-02 | — | — | US | claimed |
| CN-115380029-A | Compounds for the treatment of tuberculosis | 南洋理工大学 | 2022-11-22 | — | — | CN | claimed |
| CN-114478585-A | Nitrogen-containing fused heterocyclic compound and preparation method and application thereof | 上海青煜医药科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| WO-2021107876-A1 | COMPOUNDS FOR TREATING TUBERCULOSIS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2021-06-03 | — | — | WO | claimed |
| WO-2020238220-A1 | METHOD FOR PREPARING PAZOPANIB HYDROCHLORIDE | 济南爱思医药科技有限公司 | 2020-12-03 | — | — | WO | claimed |
| US-10689374-B1 | Pyrimidine-thiazolidinone derivatives | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2020-06-23 | — | — | US | claimed |
| CN-110407841-A | A kind of synthetic method of anti-tumor drug Rui Boxini | UNIV NATIONAL DONG HWA | 2019-11-05 | — | — | CN | claimed |
| CN-109928903-A | Quantum dot surface ligand, quantum dot film and its preparation method and application | TCL集团股份有限公司 | 2019-06-25 | — | — | CN | claimed |
| EP-1987003-A1 | PYRIDINE-2-CARBOXAMIDE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-11-05 | — | — | EP | claimed |
| EP-1747204-B1 | TRI-SUBSTITUTED UREAS AS CYTOKINE INHIBITORS | PROCTER & GAMBLE (US) | 2008-07-30 | — | — | EP | claimed |
| WO-2007093542-A1 | PYRIDINE-2-CARBOXAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-23 | — | — | WO | claimed |
| US-20070197553-A1 | 4-Aryl-pyridine-2-carboxyamide derivatives | HOFFMANN-LA ROCHE INC. | 2007-08-23 | — | — | US | claimed |
| CN-1946701-A | Trisubstituted ureas as cytokine inhibitors | PROCTER & GAMBLE (US) | 2007-04-11 | — | — | CN | claimed |
| EP-1747204-A1 | TRI-SUBSTITUTED UREAS AS CYTOKINE INHIBITORS | The Procter and Gamble Company (US) | 2007-01-31 | — | — | EP | claimed |
| WO-2005105758-A1 | TRI-SUBSTITUTED UREAS AS CYTOKINE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2005-11-10 | — | — | WO | claimed |
| US-20050239811-A1 | Tri-substituted ureas as cytokine inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-27 | — | — | US | claimed |
| EP-0644882-A1 | NOVEL PIPERZINYL-BIS(ALKYLAMINO)PYRIMIDINE DERIVATIVES AND PROCESS FOR PREPARING SAME | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1995-03-29 | — | — | EP | claimed |
| WO-1993025539-A1 | NOVEL PIPERZINYL-BIS(ALKYLAMINO)PYRIMIDINE DERIVATIVES AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1993-12-23 | — | — | WO | claimed |