Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144566 | 0.75 | NUDT1 (0.56) | SMN1; SMN2ALDH1A1RAB9AHRH4HRH3 | |
| SCHEMBL2567649 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1RAB9AHRH4HRH3 | |
| SCHEMBL28825916 | 0.72 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1RAB9AHRH4HRH3 | |
| SCHEMBL19548104 | 0.72 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1RAB9AHRH4NPC1 | |
| SCHEMBL3819188 | 0.72 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1RAB9AHRH4HRH3 | |
| SCHEMBL16840691 | 0.72 | HRH4 (0.55) | SMN1; SMN2ALDH1A1RAB9AHRH4HRH3 | |
| SCHEMBL5090089 | 0.70 | HRH4 (0.55) | SMN1; SMN2ALDH1A1RAB9AHRH4HRH3 | |
| SCHEMBL16589234 | 0.70 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1RAB9AGAAKDM4E | |
| SCHEMBL18654939 | 0.70 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1RAB9AKDM4EMEN1 | |
| SCHEMBL12168416 | 0.69 | KMO (0.71) | SMN1; SMN2ALDH1A1RAB9ANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847183-B1 | PROCESS FOR THE PREPARATION OF TRIAZOLE COMPOUNDS | Bayer Pharma AG (DE) | 2017-06-21 | — | — | EP | disclosed |